Palliative Radiotherapy for Diffuse Large B-cell Lymphoma

被引：9

作者：

Wright, Christopher M. ^{[1
]}

Koroulakis, Antony I. ^{[2
]}

Baron, Jonathan A. ^{[1
]}

Chong, Elise A. ^{[3
]}

Tseng, Yolanda D. ^{[4
]}

Kurtz, Goldie ^{[1
]}

LaRiviere, Michael ^{[1
]}

Venigalla, Sriram ^{[1
]}

Jones, Joshua A. ^{[1
]}

Maity, Amit ^{[1
]}

Mohindra, Pranshu ^{[2
]}

Plastaras, John P. ^{[1
]}

Paydar, Ima ^{[1
]}

机构：

[1] Univ Penn, Dept Radiat Oncol, 3400 Civ Ctr Blvd, Philadelphia, PA 19104 USA

[2] Univ Maryland, Dept Radiat Oncol, Baltimore, MD 21201 USA

[3] Univ Penn, Lymphoma Program, Abramson Canc Ctr, Philadelphia, PA 19104 USA

[4] Univ Washington, Dept Radiat Oncol, Seattle, WA 98195 USA

来源：

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | 2021年 / 21卷 / 10期

关键词：

Lymphoma; Diffuse large B-cell lymphoma; Palliation; Radiotherapy; Palliative radiotherapy; NON-HODGKINS-LYMPHOMA; LOW-DOSE RADIOTHERAPY; BONE-MARROW-TRANSPLANTATION; WHOLE-BRAIN RADIOTHERAPY; MODERN RADIATION-THERAPY; ORBITAL LYMPHOMA; EXTRANODAL INVOLVEMENT; REFRACTORY PRIMARY; OCULAR ADNEXA; DOUBLE-HIT;

D O I：

10.1016/j.clml.2021.05.007

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Recent improvements in chemoimmunotherapies, targeted agents, hematopoietic stem cell transplants, and cellular therapies have revolutionized treatment paradigms for patients with diffuse large B-cell lymphoma (DLBCL). Even in the relapsed or refractory setting, contemporary treatment options are delivered with curative intent and can lead to lasting remissions. Although such therapies have improved overall outcomes, they have increasingly led to a wide variety of presentations of recurrent tumors in need of palliation. Here, we review the use of radiotherapy (RT) in the palliation of DLBCL. We draw particular attention to the evolving role for hypofractionated RT and low-dose RT for DLBCL. We review the available literature on these topics and focus on commonly encountered clinical scenarios.

引用

页码：650 / 658

页数：9

共 80 条

[1] Lisocabtagene maraleucel for patients with relapsed or refractory large B-cell lymphomas (TRANSCEND NHL 001): a multicentre seamless design study [J].

Abramson, Jeremy S. ;

Palomba, M. Lia ;

Gordon, Leo I. ;

Lunning, Matthew A. ;

Wang, Michael ;

Arnason, Jon ;

Mehta, Amitkumar ;

Purev, Enkhtsetseg ;

Maloney, David G. ;

Andreadis, Charalambos ;

Sehgal, Alison ;

Solomon, Scott R. ;

Ghosh, Nilanjan ;

Albertson, Tina M. ;

Garcia, Jacob ;

Kostic, Ana ;

Mallaney, Mary ;

Ogasawara, Ken ;

Newhall, Kathryn ;

Kim, Yeonhee ;

Li, Daniel ;

Siddiqi, Tanya .

LANCET, 2020, 396 (10254) :839-852

[2] Early experience using salvage radiotherapy for relapsed/refractory non-Hodgkin lymphomas after CD19 chimeric antigen receptor (CAR) T cell therapy [J].

不详 .

BRITISH JOURNAL OF HAEMATOLOGY, 2020, 190 (01) :45-51

[3] Integrating Evidence-Based Medicine for Treatment of Spinal Metastases Into a Decision Framework: Neurologic, Oncologic, Mechanicals Stability, and Systemic Disease [J].

Barzilai, Ori ;

Laufer, Ilya ;

Yamada, Yoshiya ;

Higginson, Daniel S. ;

Schmitt, Adam M. ;

Lis, Eric ;

Bilsky, Mark H. .

JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (21) :2419-+

[4] Partial orbit irradiation achieves excellent outcomes for primary orbital lymphoma [J].

Binkley, Michael S. ;

Hiniker, Susan M. ;

Donaldson, Sarah S. ;

Hoppe, Richard T. .

PRACTICAL RADIATION ONCOLOGY, 2016, 6 (04) :255-261

[5] Proton Beam Craniospinal Irradiation Reduces Acute Toxicity for Adults With Medulloblastoma [J].

Brown, Aaron P. ;

Barney, Christian L. ;

Grosshans, David R. ;

McAleer, Mary Frances ;

de Groot, John F. ;

Puduvalli, Vinay K. ;

Tucker, Susan L. ;

Crawford, Cody N. ;

Khan, Meena ;

Khatua, Soumen ;

Gilbert, Mark R. ;

Brown, Paul D. ;

Mahajan, Anita .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2013, 86 (02) :277-284

[6] Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial [J].

Brown, Paul D. ;

Pugh, Stephanie ;

Laack, Nadia N. ;

Wefel, Jeffrey S. ;

Khuntia, Deepak ;

Meyers, Christina ;

Choucair, Ali ;

Fox, Sherry ;

Suh, John H. ;

Roberge, David ;

Kavadi, Vivek ;

Bentzen, Soren M. ;

Mehta, Minesh P. ;

Bruner, Deborah Watkins .

NEURO-ONCOLOGY, 2013, 15 (10) :1429-1437

[7] Sites of extranodal involvement are prognostic in patients with diffuse large B-cell lymphoma in the rituximab era: An analysis of the Surveillance, Epidemiology and End Results database [J].

Castillo, Jorge J. ;

Winer, Eric S. ;

Olszewski, Adam J. .

AMERICAN JOURNAL OF HEMATOLOGY, 2014, 89 (03) :310-314

[8] New insights into the epidemiology of non-Hodgkin lymphoma and implications for therapy [J].

Chihara, Dai ;

Nastoupil, Loretta J. ;

Williams, Jessica N. ;

Lee, Paul ;

Koff, Jean L. ;

Flowers, Christopher R. .

EXPERT REVIEW OF ANTICANCER THERAPY, 2015, 15 (05) :531-544

[9]

Constantine ST, 2018, 23 C EUR HEM ASS

[10] Lymphoproliferative lesions of the ocular adnexa - Analysis of 112 cases [J].

Coupland, SE ;

Krause, L ;

Delecluse, HJ ;

Anagnostopoulos, I ;

Foss, HD ;

Hummel, M ;

Bornfeld, N ;

Lee, WR ;

Stein, H .

OPHTHALMOLOGY, 1998, 105 (08) :1430-1441

← 1 2 3 4 5 6 7 8 →