FGF signalling: diverse roles during early vertebrate embryogenesis

被引：226
作者：
Dorey, Karel [1 ]
Amaya, Enrique [1 ]
机构：
[1] Univ Manchester, Fac Life Sci, Healing Fdn Ctr, Manchester M13 9PT, Lancs, England
来源：
DEVELOPMENT | 2010年 / 137卷 / 22期
基金：
英国惠康基金;
关键词：
Fibroblast growth factor; Embryogenesis; Mesoderm; Morphogenesis; Patterning; Stem cells; FIBROBLAST-GROWTH-FACTOR; EMBRYONIC STEM-CELLS; POSTERIOR NEURAL TISSUE; CENTRAL-NERVOUS-SYSTEM; LEFT-RIGHT ASYMMETRY; HOX GENE-EXPRESSION; LEFT-RIGHT AXIS; RETINOIC ACID; MESODERM INDUCTION; ANTEROPOSTERIOR AXIS;
D O I：
10.1242/dev.037689
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Fibroblast growth factor (FGF) signalling has been implicated during several phases of early embryogenesis, including the patterning of the embryonic axes, the induction and/or maintenance of several cell lineages and the coordination of morphogenetic movements. Here, we summarise our current understanding of the regulation and roles of FGF signalling during early vertebrate development.
引用
收藏
页码：3731 / 3742
页数：12
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