Structure and absolute configuration of new acidic metabolites from Stachys ehrenbergii

被引：8

作者：

Cincinelli, Raffaella ^{[1
]}

Scaglioni, Leonardo ^{[1
]}

Arnold, Nelly A. ^{[2
]}

Dallayalle, Sabrina ^{[1
]}

机构：

[1] Univ Milan, DISMA, Dipartimento Sci Mol Agroalimentari, I-20133 Milan, Italy

[2] Univ St Esprit, Beirut, Lebanon

来源：

TETRAHEDRON LETTERS | 2011年 / 52卷 / 45期

关键词：

Stachys; Secondary metabolites; Structure determination; Biflavonoids; Enantioselective synthesis; DIASTEREOSELECTIVE REDUCTION; BIOSYNTHESIS; BIFLAVONOIDS; ESTERS; ANALOG;

D O I：

10.1016/j.tetlet.2011.08.143

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two novel metabolites have been isolated from the aerial parts of Stachys ehrenberiigii. Their structures and stereochemistry were elucidated using a combination of C-13 and homo and heteronuclear 2D NMR experiments and mass analysis. The development of an enantioselective synthesis of 3-(2'-acetoxy-4-phenylbut-3'-enoylamino)propionic acid allowed to confirm the structure and assign the (R) absolute configuration at C-2' of the natural product. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：5972 / 5975

页数：4

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