Applications of microbial proteases in pharmaceutical industry: an overview

被引：30

作者：

Chanalia, Preeti ^{[1
]}

Gandhi, Dimpi ^{[1
]}

Jodha, Drukshakshi ^{[1
]}

Singh, Jasbir ^{[1
]}

机构：

[1] Kurukshetra Univ, Dept Biochem, Kurukshetra 136119, Haryana, India

来源：

REVIEWS IN MEDICAL MICROBIOLOGY | 2011年 / 22卷 / 04期

关键词：

anti-inflammatory; industrial applications; pharmaceutical industry; proteases; PROTEOLYTIC-ENZYME SERRAPEPTASE; STAPHYLOCOCCUS-AUREUS; LYSOSTAPHIN TREATMENT; STREPTOKINASE; SERRATIOPEPTIDASE; ASPARAGINASE; BIOFILMS; KNEE; PAIN;

D O I：

10.1097/MRM.0b013e3283494749

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Proteases are ubiquitous to all the living organisms. Their involvement in the life cycle of various disease causing organisms has led them to become a potential target for developing therapeutic agents against life-threatening diseases such as bacterial infection, cancer, malaria and AIDS. This review is mainly focused on the applications of microbial proteases such as serrapeptase, serrazime, lysostaphin, L-asparaginase, L-glutaminase, streptokinase, streptokinase-streptodornase and xiaflex. These enzymes are being used in the treatment of inflammation, respiratory tract disorders, cardiovascular disease and cancer. (C) 2011 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins

引用

页码：96 / 101

页数：6

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