Goats and sheep as sentinels for tick-borne encephalitis (TBE) virus - Epidemiological studies in areas endemic and non-endemic for TBE virus in Germany

被引：68

作者：

Klaus, Christine ^{[1
]}

Beer, Martin ^{[1
]}

Saier, Regine ^{[2
]}

Schau, Ute ^{[3
]}

Moog, Udo ^{[3
]}

Hoffmann, Bernd ^{[1
]}

Diller, Roland ^{[1
]}

Suess, Jochen ^{[1
]}

机构：

[1] Friedrich Loeffler Inst, Inst Bacterial Infect & Zoonoses, D-07743 Jena, Greifswald Inse, Germany

[2] Univ Hohenheim, Inst Food Sci & Biotechnol, Stuttgart, Germany

[3] Anim Hlth Serv, Jena, Germany

来源：

TICKS AND TICK-BORNE DISEASES | 2012年 / 3卷 / 01期

关键词：

Tick-borne encephalitis virus; Seroprevalence; Sheep; Goats; Natural TBEV foci; Sentinels; MONKEY MACACA-SYLVANUS; FIELD-COLLECTED TICKS; CLIMATE-CHANGE; RISK AREAS; PREVALENCE; DISEASES; HUMANS;

D O I：

10.1016/j.ttbdis.2011.09.011

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The aim of the study was to examine grazing goats and sheep as specific sentinels for characterization of the tick-borne encephalitis virus (TBEV)-related risk in an area by means of serosurveillance tests in the German federal states Baden-Wuerttemberg, Bavaria, Thuringia, North Rhine-Westphalia, Lower Saxony, Schleswig-Holstein, and Mecklenburg-West Pomerania. A total of 3590 sheep sera and 3793 goat sera was collected in 2003 and 2006-2009 and were examined by ELISA screening and confirmed by serum neutralization test. Considerable differences in seroprevalence were seen between single flocks in districts in Baden-Wuerttemberg, Bavaria, and Thuringia with values between 0 and 43% which confirmed the patchy pattern of TBEV foci that can range in size from very small to large. The here described serological screening may be a helpful tool for an early warning system of a potential TBEV risk. Testing of 1700 ticks by real-time RT-PCR in two districts in Baden-Wuerttemberg revealed only one positive tick, thus illustrating the problems of expensive and time-consuming tick collection. (C) 2011 Elsevier GmbH. All rights reserved.

引用

页码：27 / 37

页数：11

共 33 条

[11] Tick-borne Encephalitis from Eating Goat Cheese in a Mountain Region of Austria [J].

Holzmann, Heidemarie ;

Aberle, Stephan W. ;

Stiasny, Karin ;

Werner, Philipp ;

Mischak, Andreas ;

Zainer, Bernhard ;

Netzer, Markus ;

Koppi, Stefan ;

Bechter, Elmar ;

Heinz, Franz X. .

EMERGING INFECTIOUS DISEASES, 2009, 15 (10) :1671-1673

[12] Tick-borne encephalitis (TBE) virus prevalence and virus genome characterization in field-collected ticks (Ixodes ricinus) from risk, non-risk and former risk areas of TBE, and in ticks removed from humans in Germany [J].

Klaus, C. ;

Hoffmann, B. ;

Hering, U. ;

Mielke, B. ;

Sachse, K. ;

Beer, M. ;

Suess, J. .

CLINICAL MICROBIOLOGY AND INFECTION, 2010, 16 (03) :238-244

[13] Seroprevalence of tick-borne encephalitis (TBE) in naturally exposed monkeys (Macaca sylvanus) and sheep and prevalence of TBE virus in ticks in a TBE endemic area in Germany [J].

Klaus, Christine ;

Hoffmann, Bernd ;

Beer, Martin ;

Mueller, Werner ;

Stark, Bernhard ;

Bader, Wolf ;

Stiasny, Karin ;

Heinz, Franz X. ;

Suess, Jochen .

TICKS AND TICK-BORNE DISEASES, 2010, 1 (03) :141-144

[14] Can goats be used as sentinels for Tick-borne encephalitis (TBE) in non-endemic areas? Experimental studies and epizootiological observations [J].

Klaus, Christine ;

Hoffmann, Bernd ;

Moog, Udo ;

Schau, Ute ;

Beer, Martin ;

Suess, Jochen .

BERLINER UND MUNCHENER TIERARZTLICHE WOCHENSCHRIFT, 2010, 123 (11-12) :441-445

[15] Recent Epidemiology of Tick-Borne Encephalitis: An Effect of Climate Change? [J].

Korenberg, E. I. .

ADVANCES IN VIRUS RESEARCH, VOL 74, 2009, 74 :123-144

[16] Socio-economic conditions and other anthropogenic factors influencing tick-borne encephalitis incidence in the Czech Republic [J].

Kriz, B ;

Benes, C ;

Danielová, V ;

Daniel, M .

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2004, 293 :63-68

[17] Tick-borne encephalitis (TBE) in dogs [J].

Leschnik, MW ;

Kirtz, GC ;

Thalhammer, JG .

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2002, 291 :66-69

[18]

Muller W, 1997, P 4 INT POTSD S TICK, P204

[19] Foci of tick-borne diseases in southwest Germany [J].

Oehme, R ;

Hartelt, K ;

Backe, H ;

Brockmann, S ;

Kimmig, P .

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2002, 291 :22-29

[20]

Randolph S.E., 2008, VECTORS, V144, DOI [10.1186/1756-3305-I-44, DOI 10.1186/1756-3305-I-44]

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