Synthesis of prelactone B

被引：0
|
作者：
Hanefeld, U [1 ]
Hooper, AM [1 ]
Staunton, J [1 ]
机构：
[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England
来源：
SYNTHESIS-STUTTGART | 1999年 / 03期
关键词：
prelactone B; Streptomyces griseus; avermectin; polyketide synthase; aldol reaction;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Prelactone B (1a) and its isomer 1b are possible products of a truncated avermectin polyketide synthase. In order to make them available as reference compounds they were synthesized in a six-step synthesis with 56% overall yield.
引用
收藏
页码：401 / 403
页数：3
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