Feasibility of Fast-Track Surgery in Elderly Patients with Gastric Cancer

被引:55
作者
Bu, Jun [1 ,2 ]
Li, Nian [2 ]
Huang, Xiong [2 ]
He, Shan [2 ]
Wen, Jing [2 ]
Wu, Xiaoting [1 ]
机构
[1] Sichuan Univ, West China Hosp, Dept Gastrointestinal Surg, Chengdu 610064, Peoples R China
[2] Second Peoples Hosp Chengdu, Dept Gen Surg, Chengdu 610000, Sichuan Provinc, Peoples R China
关键词
Fast-track surgery; Elderly patients; Gastric cancer; IMPROVES POSTOPERATIVE RECOVERY; RANDOMIZED CLINICAL-TRIAL; ENHANCED RECOVERY; COLORECTAL SURGERY; PERIOPERATIVE CARE; DISTAL GASTRECTOMY; TRADITIONAL CARE; COLONIC SURGERY; STANDARD CARE; PROGRAM;
D O I
10.1007/s11605-015-2839-7
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The aim of this study was to investigate the role of the fast-track surgery (FTS) program in elderly patients (aged a parts per thousand yen75 years) who underwent open surgery for gastric cancer (GC) in China. A total of 256 patients with GC were randomly assigned to four groups, each of which consisted of 64 cases: the 45-74-year-old age group was subdivided into the FTS-1 group and the conventional care (CC)-1 group, and the 75-89-year-old age group was subdivided into the FTS-2 group and the CC-2 group. All patients underwent open gastrectomy by the same experienced surgical team. We compared the differences between the pairs of groups in different age ranges with respect to the postoperative recovery index, complications, and medical costs. Compared with the CC-1 group, the FTS-1 group exhibited earlier postoperative flatus, a shorter postoperative hospital stay, lower medical costs, and a decreased incidence of sore throat (P = 0.010, P = 0.000, P = 0.000, and P = 0.019, respectively). Compared with the CC-2 group, the FTS-2 group had more nausea and vomiting, stomach retention, and intestinal obstruction, as well as a higher readmission rate (P = 0.015, P = 0.011, P = 0.041, and P = 0.013, respectively). The application of FTS can significantly speed up postoperative rehabilitation, shorten the hospitalization time, and lower the medical costs for 45-74-year-old GC patients, but this procedure does not show the same benefits for elderly patients. These findings suggest that we should carefully consider whether the FTS program should be applied to elderly patients with GC.
引用
收藏
页码:1391 / 1398
页数:8
相关论文
共 53 条
[1]   Enhanced recovery pathways optimize health outcomes and resource utilization: A meta-analysis of randomized controlled trials in colorectal surgery [J].
Adamina, Michel ;
Kehlet, Henrik ;
Tomlinson, George A. ;
Senagore, Anthony J. ;
Delaney, Conor P. .
SURGERY, 2011, 149 (06) :830-840
[2]   Gastric Cancer Clinical Practice Guidelines in Oncology™ [J].
Ajani, Jaffer A. ;
Barthel, James S. ;
Bekaii-Saab, Tanios ;
Bentrem, David J. ;
D'Amico, Thomas A. ;
Das, Prajnan ;
Denlinger, Crystal ;
Fuchs, Charles S. ;
Gerdes, Hans ;
Hayman, James A. ;
Hazard, Lisa ;
Hofstetter, Wayne L. ;
Ilson, David H. ;
Keswani, Rajesh N. ;
Kleinberg, Lawrence R. ;
Korn, Michael ;
Meredith, Kenneth ;
Mulcahy, Mary F. ;
Orringer, Mark B. ;
Osarogiagbon, Raymond U. ;
Posey, James A. ;
Sasson, Aaron R. ;
Scott, Walter J. ;
Shibata, Stephen ;
Strong, Vivian E. M. ;
Washington, Mary Kay ;
Willett, Christopher ;
Wood, Douglas E. ;
Wright, Cameron D. ;
Yang, Gary .
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2010, 8 (04) :378-409
[3]   The safety of a "fast-track" program after laparoscopic colorectal surgery is comparable in older patients as in younger patients [J].
Baek, Se-Jin ;
Kim, Seon-Hahn ;
Kim, Se-Young ;
Shin, Jae-Won ;
Kwak, Jung-Myun ;
Kim, Jin .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2013, 27 (04) :1225-1232
[4]   Rapid rehabilitation in elderly patients after laparoscopic colonic resection [J].
Bardram, L ;
Funch-Jensen, P ;
Kehlet, H .
BRITISH JOURNAL OF SURGERY, 2000, 87 (11) :1540-1545
[5]   Determining factors that have an impact upon effective evidence-based pain management with older people, following colorectal surgery: an ethnographic study [J].
Brown, Donna ;
McCormack, Brendan .
JOURNAL OF CLINICAL NURSING, 2006, 15 (10) :1287-1298
[6]   Fast-track program vs traditional care in surgery for gastric cancer [J].
Chen, Zhi-Xing ;
Liu, Ae-Huey Jennifer ;
Cen, Ying .
WORLD JOURNAL OF GASTROENTEROLOGY, 2014, 20 (02) :578-583
[7]   Enhanced Recovery after Surgery (ERAS) Programs for Patients Having Colorectal Surgery: A Meta-analysis of Randomized Trials [J].
Eskicioglu, Cagla ;
Forbes, Shawn S. ;
Aarts, Mary-Anne ;
Okrainec, Allan ;
McLeod, Robin S. .
JOURNAL OF GASTROINTESTINAL SURGERY, 2009, 13 (12) :2321-2329
[8]   A multicentre comparison of a fast track or conventional postoperative protocol following laparoscopic or open elective surgery for colorectal cancer surgery [J].
Esteban, F. ;
Cerdan, F. J. ;
Garcia-Alonso, M. ;
Sanz-Lopez, R. ;
Arroyo, A. ;
Ramirez, J. M. ;
Moreno, C. ;
Morales, R. ;
Navarro, A. ;
Fuentes, M. .
COLORECTAL DISEASE, 2014, 16 (02) :134-140
[9]   Fast-track surgery could improve postoperative recovery in radical total gastrectomy patients [J].
Feng, Fan ;
Ji, Gang ;
Li, Ji-Peng ;
Li, Xiao-Hua ;
Shi, Hai ;
Zhao, Zheng-Wei ;
Wu, Guo-Sheng ;
Liu, Xiao-Nan ;
Zhao, Qing-Chuan .
WORLD JOURNAL OF GASTROENTEROLOGY, 2013, 19 (23) :3642-3648
[10]   Laparoscopy within a fast-track program enhances the short-term results after elective surgery for resectable colorectal cancer [J].
Feroci, Francesco ;
Kroening, Katrin C. ;
Lenzi, Elisa ;
Moraldi, Luca ;
Cantafio, Stefano ;
Scatizzi, Marco .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2011, 25 (09) :2919-2925