Synthesis of MUC1 peptide backbone bearing Tn and sialyl-Tn antigen for structural and functional studies with endogenous lectins

被引:0
|
作者
Ayyalasomayajula, Ramya [1 ]
Boneva, Ivet [1 ]
Whyte, Andrew, Jr. [1 ]
Cudic, Mare [1 ]
机构
[1] Florida Atlantic Univ, Charles E Schmidt Coll Sci, Dept Chem & Biochem, 777 Glades Rd, Boca Raton, FL 33431 USA
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
P085
引用
收藏
页码:1004 / 1004
页数:1
相关论文
共 48 条
  • [21] MUC2 Mucin is a Major Carrier of the Cancer-Associated Sialyl-Tn Antigen in Intestinal Metaplasia and Gastric Carcinomas
    Conze, T.
    Carvalho, A.
    Landegren, U.
    Almeida, R.
    Reis, C. A.
    David, L.
    Soderberg, O.
    HELICOBACTER, 2009, 14 (04) : 385 - 385
  • [22] MUC2 mucin is a major carrier of the cancer-associated sialyl-Tn antigen in intestinal metaplasia and gastric carcinomas
    Conze, Tim
    Carvalho, Ana Sofia
    Landegren, Ulf
    Almeida, Raquel
    Reis, Celso A.
    David, Leonor
    Soderberg, Ola
    GLYCOBIOLOGY, 2010, 20 (02) : 199 - 206
  • [23] Expression of MUC1 and MUC2 and carbohydrate antigen Tn change during malignant transformation of biliary papillomatosis
    Amaya, S
    Sasaki, M
    Watanabe, Y
    Tsui, WMS
    Tsuneyama, K
    Harada, K
    Nakanuma, Y
    HISTOPATHOLOGY, 2001, 38 (06) : 550 - 560
  • [24] A Synthetic MUC1 Glycopeptide Bearing GalNAc-Thr as a Tn Antigen Isomer Induces the Production of Antibodies against Tumor Cells
    Campo, Vanessa Leiria
    Riul, Thalita B.
    Bortot, Leandro Oliveira
    Martins-Teixeira, Maristela B.
    Marchiori, Marcelo Fiori
    Iaccarino, Emanuela
    Ruvo, Menotti
    Dias-Baruffi, Marcelo
    Carvalho, Ivone
    CHEMBIOCHEM, 2017, 18 (06) : 527 - 538
  • [25] Mucoepidermoid carcinoma-associated expression of MUC5AC, MUC5B and mucin-type carbohydrate antigen sialyl-Tn in the parotid gland
    Matse, Johannes H.
    Bharos, Wiresh K.
    Veerman, Enno C. I.
    Bloemena, Elisabeth
    Bolscher, Jan G. M.
    ARCHIVES OF ORAL BIOLOGY, 2017, 82 : 121 - 126
  • [26] A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen
    Ron Amon
    Oliver C. Grant
    Shani Leviatan Ben-Arye
    Spandana Makeneni
    Anita K. Nivedha
    Tal Marshanski
    Christoffer Norn
    Hai Yu
    John N. Glushka
    Sarel J. Fleishman
    Xi Chen
    Robert J. Woods
    Vered Padler-Karavani
    Scientific Reports, 8
  • [27] A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen
    Amon, Ron
    Grant, Oliver C.
    Ben-Arye, Shani Leviatan
    Makeneni, Spandana
    Nivedha, Anita K.
    Marshanski, Tal
    Norn, Christoffer
    Yu, Hai
    Glushka, John N.
    Fleishman, Sarel J.
    Chen, Xi
    Woods, Robert J.
    Padler-Karavani, Vered
    SCIENTIFIC REPORTS, 2018, 8
  • [28] Structural and dynamic consequences of increasing repeats in a MUC1 peptide tumor antigen
    Schuman, JT
    Grinstead, JS
    Apostolopoulos, V
    Campbell, AP
    BIOPOLYMERS, 2005, 77 (02) : 107 - 120
  • [29] Targeted antigen delivery by an anti-class II MHC VHH elicits focused αMUC1(Tn) immunity
    Fang, Tao
    Van Elssen, Catharina H. M. J.
    Duarte, Joao N.
    Guzman, Jonathan S.
    Chahal, Jasdave S.
    Ling, Jingjing
    Ploegh, Hidde L.
    CHEMICAL SCIENCE, 2017, 8 (08) : 5591 - 5597
  • [30] Mucin-type sialyl-Tn antigen is associated with PD-L1 expression and predicts poor clinical prognosis in breast cancer
    Xu, Feng
    Zhao, Hongying
    Li, Jie
    Jiang, Hongchuan
    GLAND SURGERY, 2021, 10 (07) : 2159 - +