A case report: Non-alcoholic Wernicke encephalopathy associated with polyneuropathy

被引：7

作者：

Liang, Hudong ^{[1
,2
]}

Wu, Lan ^{[3
]}

Liu, Ling-ling ^{[1
,2
]}

Han, Jinming ^{[1
,2
]}

Zhu, Jie ^{[1
,2
,4
]}

Jin, Tao ^{[1
,2
]}

机构：

[1] Jilin Univ, Hosp 1, Dept Neurol, Changchun, Jilin, Peoples R China

[2] Jilin Univ, Hosp 1, Neurosci Ctr, Changchun, Jilin, Peoples R China

[3] Jilin Univ, Hosp 1, Dept Pediat, Changchun, Jilin, Peoples R China

[4] Karolinska Inst, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden

来源：

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2017年 / 45卷 / 06期

基金：

瑞典研究理事会; 中国国家自然科学基金;

关键词：

Polyneuropathy; Wernicke encephalopathy; ACUTE AXONAL POLYNEUROPATHY; TOTAL PARENTERAL-NUTRITION; THIAMINE-DEFICIENCY; ANOREXIA-NERVOSA; KORSAKOFF-SYNDROME; CROHNS-DISEASE; PATIENT; NEUROPATHY; DIAGNOSIS; SURGERY;

D O I：

10.1177/0300060517699039

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We report a rare case of non-alcoholic Wernicke encephalopathy (WE) with polyneuropathy. A 24-year-old woman who had recently served a 4-month prison sentence and underwent a short period of dieting manifested slow response, weakness, language disorder and amnesia. Brain magnetic resonance imaging (MRI) revealed typical lesions of WE. Examination of nerve conduction velocity revealed sensory-motor axonal polyneuropathy. The patient was immediately treated with thiamine. Neurological symptoms were alleviated in a few days and abnormal signals were markedly decreased in a follow-up MRI 1 week later. Polyneuropathy symptoms ameliorated during hospital therapy and significantly improved after 4 months. This case suggests that WE may be associated with polyneuropathy in non-alcoholic patients. Early thiamine treatment in symptomatic patients may improve prognosis.

引用

页码：1794 / 1801

页数：8

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