Direct propargylic substitution of hydroxyl group in propargylic alcohols

被引：68
作者：
Kabalka, George W. [1 ]
Yao, Min-Liang
机构：
[1] Univ Tennessee, Dept Chem, Knoxville, TN 37996 USA
来源：
CURRENT ORGANIC SYNTHESIS | 2008年 / 5卷 / 01期
关键词：
D O I：
10.2174/157017908783497536
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Nucleophilic substitution reactions involving propargylic alcohols are important because the alkynyl group can be subsequently transformed into a variety of functional groups. This review summarizes recent direct substitution reactions of hydroxyl groups in propargylic alcohols, reactions that are highly desirable due to atom efficiency and environmental concerns.
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页码：28 / 32
页数：5
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