Progresses in Total Synthesis of Platencin

被引：0
|
作者：
Liu, Lian [1 ]
Zhou, Shujing [1 ]
Sun, Bingfeng [2 ]
机构：
[1] Jiamusi Univ, Sch Pharm, Jiamusi 154007, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Synthet Chem Nat Subst, Shanghai 200032, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2016年 / 36卷 / 09期
基金：
中国国家自然科学基金;
关键词：
platencin; total synthesis; synthetic strategy; PLATENSIMYCIN; ROUTE;
D O I：
10.6023/cjoc201604034
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Platencin was isolated from a new strain of Streptomyces platensis MA7339 found in a soil sample collected in Spain. It has a novel molecular structure and exhibits a broad spectrum of antibacterial activity. In this review, the progresses since 2010 in the total synthesis of platencin are summarized with an emphasis on the synthetic strategies of the routes.
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收藏
页码：2091 / 2104
页数：14
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  • [11] Discovery and Syntheses of "Superbug Challengers"-Platensimycin and Platencin
    Palanichamy, Kalanidhi
    Kaliappan, Krishna P.
    [J]. CHEMISTRY-AN ASIAN JOURNAL, 2010, 5 (04) : 668 - 703
  • [12] Oxidative Dearomatization of o-Hydroxymethylphenol and Intramolecular π4s+π2s Cycloaddition: An Expedient Synthesis of a Tricyclic Intermediate for Platencin
    Singh, Vishwakarma
    Das, Beauty
    Mobin, Shaikh M.
    [J]. SYNLETT, 2013, 24 (12) : 1583 - 1587
  • [13] Intramolecular cycloaddition in 6,6-spiroepoxycyclohexa-2,4-dienone: simple aromatics to (±)-Platencin
    Singh, Vishwakarma
    Sahu, Bharat Chandra
    Bansal, Varsha
    Mobin, Shaikh M.
    [J]. ORGANIC & BIOMOLECULAR CHEMISTRY, 2010, 8 (19) : 4472 - 4481
  • [14] Platensimycin is a selective FabF inhibitor with potent antibiotic properties
    Wang, J
    Soisson, SM
    Young, K
    Shoop, W
    Kodali, S
    Galgoci, A
    Painter, R
    Parthasarathy, G
    Tang, YS
    Cummings, R
    Ha, S
    Dorso, K
    Motyl, M
    Jayasuriya, H
    Ondeyka, J
    Herath, K
    Zhang, CW
    Hernandez, L
    Allocco, J
    Basilio, A
    Tormo, JR
    Genilloud, O
    Vicente, F
    Pelaez, F
    Colwell, L
    Lee, SH
    Michael, B
    Felcetto, T
    Gill, C
    Silver, LL
    Hermes, JD
    Bartizal, K
    Barrett, J
    Schmatz, D
    Becker, JW
    Cully, D
    Singh, SB
    [J]. NATURE, 2006, 441 (7091) : 358 - 361
  • [15] A concise formal synthesis of platencin
    Wang, Jie
    Sun, Wang-Bin
    Li, Ying-Zi
    Wang, Xuan
    Sun, Bing-Feng
    Lin, Guo-Qiang
    Zou, Jian-Ping
    [J]. ORGANIC CHEMISTRY FRONTIERS, 2015, 2 (06): : 674 - 676
  • [16] Short Route to Platencin
    Yadav, J. S.
    Goreti, Rajendar
    Pabbaraja, Srihari
    Sridhar, B.
    [J]. ORGANIC LETTERS, 2013, 15 (14) : 3782 - 3785
  • [17] Total Synthesis of (±)-Platencin
    Yoshimitsu, Takehiko
    Nojima, Shoji
    Hashimoto, Masashi
    Tanaka, Tetsuaki
    [J]. ORGANIC LETTERS, 2011, 13 (14) : 3698 - 3701
  • [18] Formal Syntheses of (±)-Platensimycin and (±)-Platencin via a Dual-Mode Lewis Acid Induced Cascade Cyclization Approach
    Zhu, Lizhi
    Zhou, Congshan
    Yang, Wei
    He, Shuzhong
    Cheng, Gui-Juan
    Zhang, Xinhao
    Lee, Chi-Sing
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2013, 78 (16) : 7912 - 7929
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