Studies towards the total synthesis of Phostriecin

被引：6
|
作者：
Kumar, Gavireddy Chaithanya [1 ]
Muralikrishna, Katta [1 ]
Satyanarayana, Vavilapalli [1 ]
Kumar, Chintakrinda Suresh [1 ]
Yadav, Jhillu Singh [1 ]
机构：
[1] Indian Inst Chem Technol, CSIR, Ctr Semiochem Div, Hyderabad 500007, Andhra Prades, India
来源：
TETRAHEDRON LETTERS | 2018年 / 59卷 / 05期
关键词：
Wittig reaction; Alkoxyallylboration; Homoallylic alcohol; Ring-closing metathesis; Antitumor natural products; PROTEIN PHOSPHATASES; METATHESIS; ANALOGS; RUCL2(=CHR)(PR(3))(2); ASSIGNMENT; SULTRIECIN; REDUCTION; KETONES;
D O I：
10.1016/j.tetlet.2017.12.068
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A synthetic approach toward the phostriecin, an antitumor natural product is, described. The key features of the present synthesis are Wittig reaction, synthesis of homoallylic alcohol using Brown's protocol (alkoxyallylboration) and RCM for the creation of unsaturated lactone moiety of phostriecin. (C) 2017 Published by Elsevier Ltd.
引用
收藏
页码：454 / 456
页数：3
相关论文
共 50 条
  • [21] Synthetic studies towards the total synthesis of opaliferin
    Opiyo, George
    Furkert, Daniel
    Brimble, Margaret
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
  • [22] STUDIES DIRECTED TOWARDS THE TOTAL SYNTHESIS OF (+/-)-HIMBACINE
    DEBAECKE, G
    DECLERCQ, PJ
    TETRAHEDRON LETTERS, 1995, 36 (41) : 7515 - 7518
  • [23] Studies towards the stereoselective total synthesis of Gliomasolide A
    Kare, Nagaraju
    Kundoor, Govinda Reddy
    Palakodety, Radha Krishna
    TETRAHEDRON LETTERS, 2019, 60 (48)
  • [24] SYNTHETIC STUDIES TOWARDS THE TOTAL SYNTHESIS OF SAFRAMYCINS
    FUKUYAMA, T
    AJECK, KL
    SACHLEBEN, RA
    YANG, LH
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1989, 197 : 113 - ORGN
  • [25] Studies towards the Total Synthesis of Cruentaren B
    Yadav, Jhillu Singh
    Reddy, Ailuri Ramesh
    CHEMISTRYSELECT, 2018, 3 (43): : 12210 - 12212
  • [26] Studies towards the total synthesis of Nagstatin.
    Tchabanenko, K
    Robertson, J
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1997, 213 : 113 - ORGN
  • [27] MODEL STUDIES TOWARDS THE TOTAL SYNTHESIS OF PACHYLACTONE
    BOOKERMILBURN, KI
    JIMENEZ, FD
    SHARPE, A
    SYNLETT, 1995, (07) : 735 - 736
  • [28] Synthetic studies towards the total synthesis of taumycin
    deGruyter, Justine N.
    Maio, William
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 245
  • [29] Studies towards the total synthesis of eunicellin diterpenes
    Pelphrey, PM
    Wright, DL
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U3044 - U3045
  • [30] Studies towards the total synthesis of Subincanadine E
    Sadlowski, Corinne M.
    Waters, Stephen P.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 248
12345