CaMKII: New tricks for an old dog

被引：8

作者：

Griffith, Leslie C. ^{[1
,2
]}

机构：

[1] Brandeis Univ, Volen Ctr Complex Syst, Dept Biol, Waltham, MA 02454 USA

[2] Brandeis Univ, Natl Ctr Behav Genom, Waltham, MA 02454 USA

来源：

CELL | 2008年 / 133卷 / 03期

关键词：

D O I：

10.1016/j.cell.2008.04.018

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Calcium/calmodulin-dependent protein kinase II (CaMKII) is a pivotal signaling molecule in both the brain and the heart. In this issue of Cell, Erickson et al. (2008) demonstrate a mechanism for CaMKII activation by reactive oxygen species that provides a direct link between kinase activation and cardiac dysfunction.

引用

页码：397 / 399

页数：4

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