Mycosporine-Like Amino Acids: Potential Health and Beauty Ingredients

被引：125

作者：

Chrapusta, Ewelina ^{[1
,2
]}

Kaminski, Ariel ^{[1
]}

Duchnik, Kornelia ^{[1
]}

Bober, Beata ^{[1
]}

Adamski, Michal ^{[1
]}

Bialczyk, Jan ^{[1
]}

机构：

[1] Jagiellonian Univ, Fac Biochem Biophys & Biotechnol, Dept Plant Physiol & Dev, Gronostajowa 7, PL-30387 Krakow, Poland

[2] Jagiellonian Univ, Inst Bot, Fac Biol & Earth Sci, Kopernika 27, PL-31501 Krakow, Poland

来源：

MARINE DRUGS | 2017年 / 15卷 / 10期

关键词：

MAAs; ultraviolet radiation; UV-absorbing compound; sunscreen; erythema; melanoma; photoaging; skin renewal; biomaterial; UV-ABSORBING COMPOUNDS; SOLAR ULTRAVIOLET-RADIATION; ANEMONE ANTHOPLEURA-ELEGANTISSIMA; EXCITED-STATE PROPERTIES; B-INDUCED SYNTHESIS; RED ALGA; ANTIOXIDANT ACTIVITY; OXIDATIVE STRESS; MARINE ORGANISMS; HUMAN SKIN;

D O I：

10.3390/md15100326

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Human skin is constantly exposed to damaging ultraviolet radiation (UVR), which induces a number of acute and chronic disorders. To reduce the risk of UV-induced skin injury, people apply an additional external protection in the form of cosmetic products containing sunscreens. Nowadays, because of the use of some chemical filters raises a lot of controversies, research focuses on exploring novel, fully safe and highly efficient natural UV-absorbing compounds that could be used as active ingredients in sun care products. A promising alternative is the application of multifunctional mycosporine-like amino acids (MAAs), which can effectively compete with commercially available filters. Here, we outline a complete characterization of these compounds and discuss their enormous biotechnological potential with special emphasis on their use as sunscreens, activators of cells proliferation, anti-cancer agents, anti-photoaging molecules, stimulators of skin renewal, and functional ingredients of UV-protective biomaterials.

引用

页数：29

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