Cardiovascular risk factors and brain white matter lesions in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)

被引：0

作者：

Vanzan Filho, Andre Bertola ^{[1
]}

Puccioni-Sohler, Marzia ^{[1
]}

机构：

[1] Univ Fed Estado Rio de Janeiro, Hosp Univ Gaffree & Guinle, Escola Med & Cirurgia, Rua Mariz & Barros 775, BR-20270004 Tijuca, RJ, Brazil

来源：

JOURNAL OF NEUROVIROLOGY | 2022年 / 28卷 / 01期

关键词：

Htlv-1-associated myelopathy; Tropical spastic paraparesis; Cardiovascular risk; Magnetic resonance imaging; Brain white matter injury; ASSOCIATION; PROFILE; HTLV;

D O I：

10.1007/s13365-022-01063-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The origin of brain white matter lesion found in HTLV-1-associated myelopathy (HAM/TSP) remains undefined. We investigated the association between white matter lesions in HAM/TSP with cardiovascular risk factors. The group of 40 patients with HAM/TSP included 60% females and mean age of 58.6 +/- 8 years old. The probability of 10-year cardiovascular disease was low in 53%, moderate in 38%, and high in 10% of the patients. There was no difference between the cardiovascular risk factors in HAM/TSP patients with and without brain lesions (p > 0.05). Our data suggest that the brain white matter abnormalities are not associated to increased cardiovascular risk in HAM/TSP.

引用

页码：168 / 171

页数：4

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