Nasal Eschar: A Warning Sign of Potentially Fatal Invasive Fungal Sinusitis in Immunocompromised Children

被引：3

作者：

Idris, Nurliza ^{[1
]}

Lim, Lynne H. Y. ^{[2
]}

机构：

[1] Hosp Sultanah Bahiyah, Alor Star 05460, Kedah, Malaysia

[2] Natl Univ Singapore, Otorhinolaryngol Head Neck Surg Dept, Singapore 117548, Singapore

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2012年 / 34卷 / 04期

关键词：

invasive fungal sinusitis; immunocompromised; biopsy; RHINOSINUSITIS;

D O I：

10.1097/MPH.0b013e31824410e3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Most invasive fungal sinusitis occurs in immunocompromised adult patients. We present the case study of a 12-year-old boy diagnosed with acute myeloblastic leukemia undergoing chemotherapy. He developed a progressive darkening discoloration over the dorsum of the nose that turned into an eschar. Nasal endoscopy revealed extensive necrotic tissue in the nasal cavity mucosa, inferior and middle turbinates, and septal cartilage that extended to the eschar of the skin over the nasal dorsum. Histopathology showed aspergillus invasive fungal rhinosinusitis.

引用

页码：E134 / E136

页数：3

共 7 条

[1] Computed tomographic findings in patients with invasive fungal sinusitis [J].

DelGaudio, JM ;

Swain, RE ;

Kingdom, TT ;

Muller, S ;

Hudgins, PA .

ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2003, 129 (02) :236-240

[2]

deShazo RD, 1997, ARCH OTOLARYNGOL, V123, P1181, DOI 10.1001/archotol.1997.01900110031005

[3] An approach to fulminant invasive fungal rhinosinusitis in the immunocompromised host [J].

Gillespie, MB ;

O'Malley, BW ;

Francis, HW .

ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 1998, 124 (05) :520-526

[4]

Gillespie MB, 2000, LARYNGOSCOPE, V110, P1832

[5] Impact of surgical treatment on paranasal fungal infections in bone marrow transplant patients [J].

Kennedy, CA ;

Adams, GL ;

Neglia, JP ;

Giebink, GS .

OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 1997, 116 (06) :610-616

[6] Aspergillosis case - Fatality rate: Systematic review of the literature [J].

Lin, SJ ;

Schranz, J ;

Teutsch, SM .

CLINICAL INFECTIOUS DISEASES, 2001, 32 (03) :358-366

[7] Prognosis of acute invasive fungal rhinosinusitis related to underlying disease [J].

Valera, Fabiana C. P. ;

do Lago, Tassiana ;

Tamashiro, Edwin ;

Yassuda, Camila Carrara ;

Silveira, Flavia ;

Anselmo-Lima, Wilma T. .

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2011, 15 (12) :E841-E844

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