SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF ALKYLAMMONIUM SALTS OF N,N′-MALONYL-BIS-P-AMINOBENZOIC ACID

被引：2

作者：

Shepel', F. G. ^{[1
]}

Zozulya, R. N. ^{[2
]}

Shepel', D. F. ^{[1
]}

Makaev, F. Z. ^{[1
]}

机构：

[1] Natl Acad Sci Moldova, Inst Chem, Chishinau, Moldova

[2] St Petersburg State Chemicopharmaceut Acad, St Petersburg, Russia

来源：

PHARMACEUTICAL CHEMISTRY JOURNAL | 2010年 / 44卷 / 09期

关键词：

ammonium salts of N; N '-malonyl-bis-p-aminobenzoic acid; synthesis; hypotensive effect; antiarrhythmic activity; AQUEOUS-SOLUTIONS;

D O I：

10.1007/s11094-010-0493-7

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of ammonium salts of N,N'-malonyl-bis-p-aminobenzoic acid with some alkylamines have been obtained. It is established that these compounds possess hypotensive, antiarrhythmic, and anticoagulative activities depending on the structure of the alkylamine constituents.

引用

页码：469 / 471

页数：3

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