NaBH4-mediated facile reduction of esters of Baylis-Hillman adducts:: An efficient approach to substituted propane-1,3-diols

被引：17

作者：

Patra, A ^{[1
]}

Batra, S ^{[1
]}

Bhaduri, AP ^{[1
]}

机构：

[1] Cent Drug Res Inst, Div Med Chem, Lucknow 226001, Uttar Pradesh, India

来源：

SYNLETT | 2003年 / 11期

关键词：

Baylis-Hillman reaction; NaBH4; reduction; ester; propane-1,3-diol;

D O I：

10.1055/s-2003-40992

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reduction of the ester group in the Baylis-Hillman adducts by NaBH4 reduction is facilitated by the secondary hydroxyl group present at their beta-position. This method is efficient for the preparation of substituted propane-1,3-diols.

引用

页码：1611 / 1614

页数：4

共 14 条

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