Adjuvant Therapy for Melanoma: A Surgical Perspective

被引:12
作者
Sondak, Vernon K. [1 ,2 ,3 ]
Gonzalez, Ricardo J. [1 ,2 ,4 ]
Kudchadkar, Ragini [1 ,2 ]
机构
[1] Univ S Florida, Coll Med, H Lee Moffitt Canc Ctr & Res Inst, Dept Cutaneous Oncol, Tampa, FL 33612 USA
[2] Univ S Florida, Coll Med, Dept Oncol Sci, Tampa, FL 33612 USA
[3] Univ S Florida, Coll Med, Dept Surg, Tampa, FL 33612 USA
[4] Univ S Florida, Coll Med, H Lee Moffitt Canc Ctr & Res Inst, Dept Sarcoma Oncol, Tampa, FL 33612 USA
关键词
Melanoma; Adjuvant therapy; Interferon; Vaccines; GM-CSF; Ipilimumab; HIGH-RISK MELANOMA; ISOLATED LIMB INFUSION; COOPERATIVE-ONCOLOGY-GROUP; SENTINEL-NODE BIOPSY; DOSE INTERFERON-ALPHA-2B; STAGE-III; PEGYLATED INTERFERON-ALPHA-2B; 1.5; MM; TRIAL; PERFUSION;
D O I
10.1016/j.soc.2010.09.001
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Adjuvant therapy is commonly used in melanoma because recurrence after surgery usually results in the patient's eventual death. Surgeons have a profound influence on patients' decisions regarding adjuvant therapy, beginning with providing a clear understanding of the risk of specific types of recurrence. This review summarizes the potential oncologic benefits and relevant toxicities of adjuvant systemic therapies for melanoma that are currently available and under investigation.
引用
收藏
页码:105 / +
页数:11
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