Design and synthesis of isoxazole and isoxazoline linkage for replacement of nucleotide phosphodiester

被引：17

作者：

Kim, SJ ^{[1
]}

Lee, JY ^{[1
]}

Kim, BH ^{[1
]}

机构：

[1] Pohang Univ Sci & Technol, Ctr Biofunct Mol, Dept Chem, Pohang 790784, South Korea

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1998年 / 8卷 / 11期

关键词：

D O I：

10.1016/S0960-894X(98)00210-8

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Synthetic routes for oligonucleotides which have isoxazoline or isoxazole linkage have been developed, and di- and tri-nucleotides with thymine bases have been prepared. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1313 / 1316

页数：4

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