Postoperative sepsis after colorectal surgery: a prospective single-center observational study and review of the literature

被引:56
作者
Mulita, Francesk [1 ]
Liolis, Elias [2 ]
Akinosoglou, Karolina [3 ]
Tchabashvili, Levan [1 ]
Maroulis, Ioannis [1 ]
Kaplanis, Charalampos [1 ]
Vailas, Michail [1 ]
Panos, George [3 ]
机构
[1] Gen Univ Hosp, Dept Gen Surg, Patras, Greece
[2] Gen Univ Hosp, Dept Internal Med, Div Oncol, Patras, Greece
[3] Gen Univ Hosp, Dept Internal Med & Infect Dis, Patras, Greece
来源
GASTROENTEROLOGY REVIEW-PRZEGLAD GASTROENTEROLOGICZNY | 2022年 / 17卷 / 01期
关键词
sepsis; colorectal surgery; postoperative complication; COMPLICATIONS; DEFINITIONS;
D O I
10.5114/pg.2021.106083
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Introduction: Postoperative sepsis represents a significant problem in colorectal surgery patients. Aim: To identify the etiology as well as the risk factors associated with the development of postoperative sepsis, based on prospective data of patients undergoing colorectal surgery at a single large-volume institution. Material and methods: Between November 2019 and February 2021, 141 patients underwent an elective operation for colorectal cancer at a tertiary hospital center. The following variables were recorded for each patient: age, gender, American Society of Anesthesiologists Classification (ASA class), duration of surgery, surgical approach, comorbidities (diabetes, cardiovascular disease, respiratory disease). Univariate analysis was performed using chi(2) tests for categorical variables. Results: A total of 69 males and 72 females were enrolled. Postoperative sepsis was diagnosed in 18 (12.77%) cases, with anastomotic leakage being the most frequent cause (3.55%). There was no statistically significant difference in the presence of sepsis among patients when gender, surgical approach, duration of surgery, and respiratory disease were taken into account. Sixty-nine patients were > 65 years old, with sepsis being statistically significant in this group (p = 0.034). Furthermore, patients with ASA class <= 2 developed postoperative sepsis less frequently than patients with advanced ASA scores (p = 0.008). Diabetes and cardiovascular disease also reach statistical significance; sepsis was more frequent in this group of patients (p = 0.013 and p = 0.009, respectively). Conclusions: Following colorectal cancer procedures, postoperative sepsis was significantly more common among patients over 65 years old, ASA score > 2, and also with associated comorbidities such as diabetes and cardiovascular disease.
引用
收藏
页码:47 / 51
页数:5
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