Effects of Afobazole on the Content of Neurotransmitter Amino Acids in the Striatum in Global Transient Ischemia

被引：0

作者：

Baykova, V. S. ^{[1
]}

Kadnikov, I. A. ^{[1
]}

Voronin, M. V. ^{[1
]}

Ganshina, T. S. ^{[1
]}

Gnezdilova, A. V. ^{[1
]}

Gorbunov, A. A. ^{[1
]}

Mirzoyan, P. C. ^{[1
]}

Seredenin, S. B. ^{[1
]}

机构：

[1] Russian Acad Med Sci, VV Zakusov Inst Pharmacol, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2011年 / 151卷 / 05期

关键词：

afobazole; amino acids; global ischemia; striatum; FOREBRAIN ISCHEMIA; ACTIVATION; TAURINE; MECHANISMS; OCCLUSION; TISSUE; RATS;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Anxiolytic agent afobazole (10 mg/kg intraperitoneally) 24 h after ischemia restores impaired balance of excitatory and inhibitory amino acids in the striatum of mongrel rats, normalizes their content to control levels, and activates endogenous taurine-dependent system of neuroprotection.

引用

页码：593 / 596

页数：4

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