MicroRNAs in rheumatoid arthritis

被引：84

作者：

Ceribelli, Angela ^{[1
]}

Nahid, Md A. ^{[1
]}

Satoh, Minoru ^{[2
,3
]}

Chan, Edward K. L. ^{[1
]}

机构：

[1] Univ Florida, Dept Oral Biol, Gainesville, FL 32610 USA

[2] Univ Florida, Dept Med, Div Rheumatol & Clin Immunol, Gainesville, FL 32610 USA

[3] Univ Florida, Dept Pathol Immunol & Lab Med, Gainesville, FL 32610 USA

来源：

FEBS LETTERS | 2011年 / 585卷 / 23期

基金：

美国国家卫生研究院;

关键词：

Autoimmunity; Innate immunity; Rheumatoid arthritis; microRNA; miR-146a; ANTICITRULLINATED PROTEIN ANTIBODIES; MESSENGER-RNAS; PORPHYROMONAS-GINGIVALIS; SYNOVIAL FIBROBLASTS; PERIODONTAL-DISEASE; DNA HYPOMETHYLATION; MEDIATED REGULATION; ALTERED EXPRESSION; GW/P-BODIES; T-CELLS;

D O I：

10.1016/j.febslet.2011.05.020

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Rheumatoid arthritis (RA) is a chronic and severe autoimmune disease that affects joint tissues, bone, and cartilage. However, the pathogenesis of RA is still unclear. Autoantibodies such as rheumatoid factor and anti-cyclic citrullinated peptide are useful tools for early diagnosis, monitoring disease activity, and predicting prognosis. Recently, many groups have focused their attention on the role of microRNAs in the pathogenesis of RA, as well as a potential biomarker to monitor RA. In fact, the expression of some microRNAs, such as miR-146a, is upregulated in different cell types and tissues in RA patients. MicroRNAs in RA could also be considered as possible future targets for new therapeutic approaches. (C) 2011 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

引用

页码：3667 / 3674

页数：8

共 88 条

[1] Compensatory anti-inflammatory response syndrome [J].

Adib-Conquy, Minou ;

Cavaillon, Jean-Marc .

THROMBOSIS AND HAEMOSTASIS, 2009, 101 (01) :36-47

[2] MicroRNAs as biomarkers in rheumatic diseases [J].

Alevizos, Ilias ;

Illei, Gabor G. .

NATURE REVIEWS RHEUMATOLOGY, 2010, 6 (07) :391-398

[3] Bruton's Tyrosine Kinase Is Involved in miR-346-Related Regulation of IL-18 Release by Lipopolysaccharide-Activated Rheumatoid Fibroblast-Like Synoviocytes [J].

Alsaleh, Ghada ;

Suffert, Guillaume ;

Semaan, Noha ;

Juncker, Tom ;

Frenzel, Laurent ;

Gottenberg, Jacques-Eric ;

Sibilia, Jean ;

Pfeffer, Sebastien ;

Wachsmann, Dominique .

JOURNAL OF IMMUNOLOGY, 2009, 182 (08) :5088-5097

[4] A uniform system for microRNA annotation [J].

Ambros, V ;

Bartel, B ;

Bartel, DP ;

Burge, CB ;

Carrington, JC ;

Chen, XM ;

Dreyfuss, G ;

Eddy, SR ;

Griffiths-Jones, S ;

Marshall, M ;

Matzke, M ;

Ruvkun, G ;

Tuschl, T .

RNA, 2003, 9 (03) :277-279

[5] THE AMERICAN-RHEUMATISM-ASSOCIATION 1987 REVISED CRITERIA FOR THE CLASSIFICATION OF RHEUMATOID-ARTHRITIS [J].

ARNETT, FC ;

EDWORTHY, SM ;

BLOCH, DA ;

MCSHANE, DJ ;

FRIES, JF ;

COOPER, NS ;

HEALEY, LA ;

KAPLAN, SR ;

LIANG, MH ;

LUTHRA, HS ;

MEDSGER, TA ;

MITCHELL, DM ;

NEUSTADT, DH ;

PINALS, RS ;

SCHALLER, JG ;

SHARP, JT ;

WILDER, RL ;

HUNDER, GG .

ARTHRITIS AND RHEUMATISM, 1988, 31 (03) :315-324

[6] Malignancy and biologic therapy in rheumatoid arthritis [J].

Askling, Johan ;

Bongartz, Tim .

CURRENT OPINION IN RHEUMATOLOGY, 2008, 20 (03) :334-339

[7] Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs [J].

Babiarz, Joshua E. ;

Ruby, J. Graham ;

Wang, Yangming ;

Bartel, David P. ;

Blelloch, Robert .

GENES & DEVELOPMENT, 2008, 22 (20) :2773-2785

[8] MicroRNAs: new regulators of immune cell development and function [J].

Baltimore, David ;

Boldin, Mark P. ;

O'Connell, Ryan M. ;

Rao, Dinesh S. ;

Taganov, Konstantin D. .

NATURE IMMUNOLOGY, 2008, 9 (08) :839-845

[9] MicroRNAs: Target Recognition and Regulatory Functions [J].

Bartel, David P. .

CELL, 2009, 136 (02) :215-233

[10] Mammalian mirtron genes [J].

Berezikov, Eugene ;

Chung, Wei-Jen ;

Willis, Jason ;

Cuppen, Edwin ;

Lai, Eric C. .

MOLECULAR CELL, 2007, 28 (02) :328-336

← 1 2 3 4 5 6 7 8 9 →