Prevalence of antiretroviral drug genotypic resistance among HIV patients in Cuenca, Spain

被引：0

作者：

Rodriguez-Escudero, M. J. ^{[1
]}

de Medio, E. Prada

Herranz, C. Rosa ^{[2
]}

Medina, M. C. Martinez

Gutierrez, R. Franquelo

机构：

[1] Hosp Virgen Luz, Unidad Microbiol, Serv Anal Clin, ES-16002 Cuenca, Spain

[2] Hosp Virgen Luz, Med Interna Serv, Unidad Enfermedades Infecciosas, ES-16002 Cuenca, Spain

来源：

REVISTA ESPANOLA DE QUIMIOTERAPIA | 2007年 / 20卷 / 02期

关键词：

HIV; resistance; mutations;

D O I：

暂无

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The aims were to assess the prevalence of resistances to antiretroviral drugs in HIV patients in the province of Cuenca and to determine the most frequently detected primary resistances. A total of 79 samples collected from April 2000 to July 2004 were analyzed. Resistance was detected using the genotypic technique VERSANTTM HIV1 (LiPA). Mutations more frequently found were M184V in the reverse transcriptase gene and V82A in the protease gene. The prevalence of primary resistances was 39.4%. Mutations more frequently detected were similar to those reported by other authors. The rate of primary resistance was higher than those found by other authors in Spain.

引用

页码：203 / 205

页数：3

共 50 条

[41] Mutations associated with genotypic resistance to antiretroviral therapy in treatment naive HIV-1 infected patients in Greece [J].

Magiorkinis, E ;

Paraskevis, D ;

Magiorkinis, G ;

Chryssou, S ;

Chini, M ;

Lazanas, M ;

Paparizos, V ;

Saroglou, G ;

Antoniadou, A ;

Giamarellou, E ;

Karafoulidou, A ;

Hatzakis, A .

VIRUS RESEARCH, 2002, 85 (01) :109-115

[42] HIV-I genotypic drug resistance in patients with virological failure to single-tablet antiretroviral regimens in southern Taiwan [J].

Tsai, Hung-Chin ;

Chen, I-Tzu ;

Lee, Susan Shin-Jung ;

Chen, Yao-Shen .

INFECTION AND DRUG RESISTANCE, 2018, 11 :1061-1071

[43] Low Prevalence of Transmitted HIV Type 1 Drug Resistance Among Antiretroviral-Naive Adults in a Rural HIV Clinic in Kenya [J].

Hassan, Amin S. ;

Mwaringa, Shalton M. ;

Obonyo, Clare A. ;

Nabwera, Helen M. ;

Sanders, Eduard J. ;

de Wit, Tobias F. Rinke ;

Cane, Patricia A. ;

Berkley, James A. .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 2013, 29 (01) :129-135

[44] Prevalence and characteristics of HIV drug resistance among antiretroviral treatment (ART) experienced adolescents and young adults living with HIV in Ndola, Zambia [J].

Miti, Sam ;

Handema, Ray ;

Mulenga, Lloyd ;

Mwansa, Jonathan K. ;

Abrams, Elizabeth ;

Frimpong, Christiana ;

Burke, Virginia M. ;

Zulu, Mangani ;

Siwingwa, Mpanji ;

Mwakazanga, David ;

Kalibala, Sam ;

Denison, Julie A. .

PLOS ONE, 2020, 15 (08)

[45] HIV drug resistance among nave HIV-infected patients in Iran [J].

Farrokhi, Molood ;

Gholami, Mohammad ;

Mohraz, Minoo ;

McFarland, Willi ;

Baesi, Kazem ;

Abbasian, Ladan .

JOURNAL OF RESEARCH IN MEDICAL SCIENCES, 2019, 24

[46] High Drug Resistance Prevalence among Vertically HIV-Infected Patients Transferred from Pediatric Care to Adult Units in Spain [J].

de Mulder, Miguel ;

Yebra, Gonzalo ;

Navas, Adriana ;

Isabel de Jose, Maria ;

Dolores Gurbindo, Maria ;

Isabel Gonzalez-Tome, Maria ;

Jose Mellado, Maria ;

Saavedra-Lozano, Jesus ;

Angeles Munoz-Fernandez, Maria ;

Jimenez de Ory, Santiago ;

Tomas Ramos, Jose ;

Holguin, Africa .

PLOS ONE, 2012, 7 (12)

[47] HIV-1 genotypic diversity and prevalence of drug resistance among treatment naïve HIV-infected individuals in Chengdu of China [J].

Peibin Zeng ;

Yu Liu ;

Miao He ;

Zhan Gao ;

Ya Zhou ;

Guohui Bian ;

Hua Shan ;

Jingxing Wang .

Virus Genes, 2013, 47 :408-413

[48] HIV drug resistance among patients experiencing antiretroviral therapy failure in Russia, 2019-2021 [J].

Sivay, Mariya, V ;

Maksimenko, Lada, V ;

Nalimova, Tatiana M. ;

Nefedova, Anastasiya A. ;

Osipova, Irina P. ;

Krikliv, Nadezda P. ;

Gashnikov, Mariya P. ;

Ekushov, Vasiliy E. ;

Totmenin, Alexei, V ;

Kapustin, Dmitriy, V ;

Pozdnyakova, Larisa L. ;

Skudarnov, Sergey E. ;

Ostapova, Tatyana S. ;

Yaschenko, Svetlana, V ;

Nazarova, Olga I. ;

Shevchenko, Valery V. ;

Ilyina, Elena A. ;

Novikova, Olga A. ;

Agafonov, Aleksander P. ;

Gashnikova, Natalya M. .

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2024, 63 (02)

[49] HIV drug resistance and its associated factors among patients during interruption of antiretroviral therapy in China [J].

Zuo, Zhongbao ;

Huang, Wei ;

Liu, Lei ;

Li, Miaomiao ;

Chen, Hongli ;

Feng, Yi ;

Liao, Lingjie ;

Shao, Yiming ;

Ruan, Yuhua ;

Wu, Jing ;

Xing, Hui .

FRONTIERS IN MICROBIOLOGY, 2025, 16

[50] Viraemia and HIV-1 drug resistance mutations among patients receiving antiretroviral treatment in Mozambique [J].

Maldonado, F. ;

Biot, M. ;

Roman, F. ;

Masquelier, C. ;

Anapenge, M. ;

Bastos, R. ;

Chuquela, H. C. ;

Arendt, V. ;

Schmit, J. C. ;

Zachariah, R. .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2009, 103 (06) :607-612

← 1 2 3 4 5 →