Chronic thromboembolic pulmonary hypertension (CTEPH): Updated Recommendations of the Cologne Consensus Conference 2011

被引：76

作者：

Wilkens, Heinrike ^{[1
]}

Lang, Irene ^{[2
]}

Behr, Juergen ^{[3
]}

Berghaus, Thomas ^{[4
]}

Grohe, Christian ^{[5
]}

Guth, Stefan ^{[6
]}

Hoeper, Marius M. ^{[7
]}

Kramm, Thorsten ^{[6
]}

Krueger, Ulrich ^{[8
]}

Langer, Frank ^{[9
]}

Rosenkranz, Stephan ^{[10
]}

Schaefers, Hans-Joachim ^{[9
]}

Schmidt, Matthias ^{[11
]}

Seyfarth, Hans-Juergen ^{[12
]}

Wahlers, Thorsten ^{[13
]}

Worth, Heinrich ^{[14
]}

Mayer, Eckhard ^{[6
]}

机构：

[1] Saarland Univ Hosp, Med Clin 5, Clin Internal Med 5, D-66421 Homburg, Germany

[2] Med Univ Vienna, Dept Cardiol, Clin Internal Med 2, Vienna, Austria

[3] Univ Hosp Bergmannsheil, Med Clin 3, Bochum, Germany

[4] Augsburg Hosp, Med Clin 1, Augsburg, Germany

[5] Protestant Lung Clin Berlin Buch, Clin Resp Med, Berlin, Germany

[6] Kerckhoff Clin, Dept Thorac Surg, Bad Nauheim, Germany

[7] Hannover Med Sch, Clin Resp Med, D-3000 Hannover, Germany

[8] Heart Ctr Duisburg, Duisburg, Germany

[9] Saarland Univ Hosp, Clin Thorac & Cardiovasc Surg, Homburg, Germany

[10] Univ Cologne, Ctr Heart, Clin Internal Med 3, Cologne, Germany

[11] Univ Hosp Cologne, Dept Nucl Med, Cologne, Germany

[12] Leipzig Univ Hosp, Dept Resp Med, Leipzig, Germany

[13] Cologne Univ Hosp, Clin Heart & Thorac Surg, Cologne, Germany

[14] Hosp Furth, Med Clin 1, Furth, Germany

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2011年 / 154卷

关键词：

Chronic thromboembolic pulmonary hypertension; Diagnosis; Treatment; ENDARTERECTOMY SURGERY; BOSENTAN THERAPY; RISK-FACTORS; DIAGNOSIS; GUIDELINES; EMBOLISM; THROMBOENDARTERECTOMY; MANAGEMENT; PERFUSION; OUTCOMES;

D O I：

10.1016/S0167-5273(11)70493-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In the 2009 European Guidelines on the diagnosis and treatment of pulmonary hypertension (PH), one section covers aspects of pathophysiology, diagnosis and treatment of chronic thromboembolic pulmonary hypertension (CTEPH). The practical implementation of the guidelines for this disease is of crucial importance, because CTEPH is a subset of PH which can potentially be cured by pulmonary endarterectomy (PEA). Nowadays, CTEPH is commonly underdiagnosed and not properly managed. Any patient with unexplained PH should be evaluated for the presence of CTEPH, and a ventilation/perfusion (V/Q) lung scan is recommended as screening method of choice. If the V/Q scan or CT angiography reveals signs of CTEPH, the patient should be referred to a specialized center with expertise in the medical and surgical management of this disease. Every case has to be reviewed by an experienced PEA surgeon for the assessment of operability. In this updated recommendation, important contents of the European guidelines were commented, and more recent information regarding diagnosis and treatment was added. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

引用

页码：S54 / S60

页数：7

共 43 条

[1]

Bajc M, 2009, EUR J NUCL MED MOL I, V36, P1528, DOI 10.1007/s00259-009-1169-y

[2]

Bajc M, 2009, EUR J NUCL MED MOL I, V36, P1356, DOI 10.1007/s00259-009-1170-5

[3] Incidence of chronic thromboembolic pulmonary hypertension after a first episode of pulmonary embolism [J].

Becattini, Cecilia ;

Agnelli, Giancarlo ;

Pesavento, Raffaele ;

Silingardi, Mauro ;

Poggio, Renzo ;

Taliani, Maria Rita ;

Ageno, Walter .

CHEST, 2006, 130 (01) :172-175

[4]

Bonderman D, 2005, CHEST, V128, P2599, DOI 10.1378/chest.128.4.2599

[5] Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension [J].

Bonderman, D ;

Jakowitsch, J ;

Adlbrecht, C ;

Schemper, M ;

Kyrle, PA ;

Schönauer, V ;

Exner, M ;

Klepetko, E ;

Kneussl, MR ;

Maurer, G ;

Lang, I .

THROMBOSIS AND HAEMOSTASIS, 2005, 93 (03) :512-516

[6] High prevalence of elevated clotting factor VIII in chronic thromboembolic pulmonary hypertension [J].

Bonderman, D ;

Turecek, PL ;

Jakowitsch, J ;

Weltermann, A ;

Adlbrecht, C ;

Schneider, B ;

Kneussl, M ;

Rubin, LJ ;

Kyrle, PA ;

Klepetko, W ;

Maurer, G ;

Lang, IM .

THROMBOSIS AND HAEMOSTASIS, 2003, 90 (03) :372-376

[7] Risk factors for chronic thromboembolic pulmonary hypertension [J].

Bonderman, D. ;

Wilkens, H. ;

Wakounig, S. ;

Schaefers, H-J. ;

Jansa, P. ;

Lindner, J. ;

Simkova, I. ;

Martischnig, A. M. ;

Dudczak, J. ;

Sadushi, R. ;

Skoro-Sajer, N. ;

Klepietko, W. ;

Lang, I. M. .

EUROPEAN RESPIRATORY JOURNAL, 2009, 33 (02) :325-331

[8] Predictors of outcome in chronic thromboembolic pulmonary hypertension [J].

Bonderman, Diana ;

Skoro-Sajer, Nika ;

Jakowitsch, Johannes ;

Adlbrecht, Christopher ;

Dunkler, Daniela ;

Taghavi, Sharokh ;

Klepetko, Walter ;

Kneussl, Meinhard ;

Lang, Irene M. .

CIRCULATION, 2007, 115 (16) :2153-2158

[9] Continuous intravenous epoprostenol for chronic thromboembolic pulmonary hypertension [J].

Bresser, P ;

Fedullo, PF ;

Auger, WR ;

Channick, RN ;

Robbins, IM ;

Kerr, KM ;

Jamieson, SW ;

Rubin, LJ .

EUROPEAN RESPIRATORY JOURNAL, 2004, 23 (04) :595-600

[10] Improved outcomes in medically and surgically treated chronic thromboembolic pulmonary hypertension [J].

Condliffe, Robin ;

Kiely, David G. ;

Gibbs, J. Simon R. ;

Corris, Paul A. ;

Peacock, Andrew J. ;

Jenkins, David P. ;

Hodgkins, Denise ;

Goldsmith, Kim ;

Hughes, Rodney J. ;

Sheares, Karen ;

Tsui, Steven S. L. ;

Armstrong, Iain J. ;

Torpy, Chantal ;

Crackett, Rachel ;

Carlin, Christopher M. ;

Das, Clare ;

Coghlan, J. Gerry ;

Pepke-Zaba, Joanna .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2008, 177 (10) :1122-1127

← 1 2 3 4 5 →