Endoplasmic reticulum in viral infection

被引:15
作者
Bagchi, Parikshit [1 ]
机构
[1] Univ Michigan, Sch Med, Dept Cell & Dev Biol, Ann Arbor, MI 48109 USA
来源
BIOLOGY OF THE ENDOPLASMIC RETICULUM | 2020年 / 350卷
关键词
OXYSTEROL-BINDING-PROTEIN; 4-KINASE III ALPHA; VIRUS-REPLICATION; DENGUE VIRUS; RNA REPLICATION; QUALITY-CONTROL; ULTRASTRUCTURAL CHARACTERIZATION; POLIOVIRUS INFECTION; DISULFIDE-ISOMERASE; MEMBRANE-PROTEINS;
D O I
10.1016/bs.ircmb.2019.10.005
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Virus exploits host cellular machinery to replicate and form new viral progeny and endoplasmic reticulum (ER) plays central role in the interplay between virus and host cell. Here I will discuss how cellular functions of ER being utilized by viruses from different families during different stages of pathogenesis. Flow of knowledge related to this area of research based on interdisciplinary approach, using biochemical and cell biological assays coupled with advanced microscopy strategies, is pushing our understanding of the virus-ER interaction during infection to the next level.
引用
收藏
页码:265 / 284
页数:20
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