Can maternal-child microbial seeding interventions improve the health of infants delivered by Cesarean section?

被引：29

作者：

Hourigan, Suchitra K. ^{[1
]}

Dominguez-Bello, Maria Gloria ^{[2
]}

Mueller, Noel T. ^{[3
]}

机构：

[1] NIAID, Clin Microbiome Unit CMU, Lab Host Immun & Microbiome, NIH, 9000 Rockville Pike, Bethesda, MD 20892 USA

[2] Rutgers State Univ, Dept Biochem & Microbiol, New Brunswick, NJ 08854 USA

[3] Johns Hopkins Univ, Dept Epidemiol, Bloomberg Sch Publ Hlth, Baltimore, MD 21218 USA

来源：

CELL HOST & MICROBE | 2022年 / 30卷 / 05期

基金：

美国国家卫生研究院;

关键词：

BORN INFANTS; MULTIPLE; SHAPES;

D O I：

10.1016/j.chom.2022.02.014

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Maternal-child microbial seeding interventions expose Cesarean-section (C-section)-delivered infants to the maternal microbiome they bypass during Cesarean delivery. It is theorized such interventions restore the microbiome and normalize immune development to reduce the occurrence of C-section-associated inflammatory conditions. Here we discuss the rationale, evidence, and controversies surrounding such interventions.

引用

页码：607 / 611

页数：5

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