Charting the Roadmap of T Cell Exhaustion

被引：16
作者：
Chu, Talyn [1 ]
Zehn, Dietmar [1 ]
机构：
[1] Tech Univ Munich, TUM Sch Life Sci Weihenstephan, Div Anim Physiol & Immunol, Freising Weihenstephan, Germany
来源：
IMMUNITY | 2020年 / 52卷 / 05期
关键词：
D O I：
10.1016/j.immuni.2020.04.019
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Exposure to chronic infection or malignant tumors triggers the differentiation of functionally impaired, so-called exhausted T cells. In this issue of Immunity, Beltra et al. reveal a multi-step developmental process that defines how T cells transition from proliferating progenitors into terminally differentiated exhausted T cells.
引用
收藏
页码：724 / 726
页数：3
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