Essential Oil of Myrtus communis Inhibits Inflammation in Rats by Reducing Serum IL-6 and TNF-α

被引：0

作者：

Maxia, Andrea ^{[1
]}

Frau, Maria Assunta ^{[1
]}

Falconieri, Danilo ^{[2
,4
]}

Karchuli, Manvendra Singh ^{[3
]}

Kasture, Sanjay ^{[3
]}

机构：

[1] Univ Cagliari, Dept Life & Environm Sci, Bot & Bot Garden Div, Cagliari, Italy

[2] Univ Cagliari, Dept Chem, Monserrato, Italy

[3] Pinnacle Biomed Res Inst, Bhopal, India

[4] Ist Tecn M Giua, Cagliari, Italy

来源：

NATURAL PRODUCT COMMUNICATIONS | 2011年 / 6卷 / 10期

关键词：

Myrtus communis; MPO; edema; TNF-alpha; IL-6; ANTIINFLAMMATORY ACTIVITY; EXTRACT;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The topical antiinflammatory activity of the essential oil of Myrtus communis L. was studied using croton oil induced ear edema and myeloperoxidase (MPO) activity in mice, and cotton pellet induced granuloma, and serum tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) in rats. On topical application, the oil exhibited a significant decrease in the ear edema as well as MPO activity. The oil also inhibited cotton pellet-induced granuloma and serum TNF-alpha and IL-6. It can be concluded that the essential oil of Myrtus communis reduces leukocyte migration to the damaged tissue and exhibits antiinflammatory activity.

引用

页码：1545 / 1548

页数：4

共 22 条

[1]

Alem Genetu, 2008, Ethiop Med J, V46, P63

[2] Antibacterial galloylated alkylphloroglucinol glucosides from myrtle (Myrtus communis) [J].