Surface modification of polymeric vesicles via host-guest inclusion complexation

被引:44
作者
Guo, Mingyu [1 ,2 ]
Jiang, Ming [1 ,2 ]
Zhang, Guangzhao [3 ,4 ]
机构
[1] Fudan Univ, Minist Educ, Key Lab Mol Engn Polymers, Shanghai 200433, Peoples R China
[2] Fudan Univ, Dept Macromol Sci, Shanghai 200433, Peoples R China
[3] Univ Sci & Technol China, Dept Chem Phys, Hefei 230026, Peoples R China
[4] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Peoples R China
基金
美国国家科学基金会;
关键词
D O I
10.1021/la802126w
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We have prepared a novel kind of building block (CD-PI-CD) of polyether imide (PI) with beta-cyclodextrin (beta-CD) at the both ends that self-assembles into vesicles in water. The vesicles are "reactive" in supramolecular chemistry because the host groups of beta-CD equally distribute on the inside and outside surfaces of the vesicles. Isothermal titration calorimetry (ITC) and static light scattering (SLS) studies demonstrate that both the inner and outer surfaces of the vesicles can be further modified noncovalently with adamantane-ended polyethlene glycol (Ada-PEG) via a host-guest inclusion interaction between beta-CD and adamantane.
引用
收藏
页码:10583 / 10586
页数:4
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