EXPANDing the Donor Pool: Quantifying the Potential Impact of a Portable Organ-Care System for Expanded Criteria Heart Donation

被引：16

作者：

Jawitz, Oliver K. ^{[1
]}

Devore, Adam D. ^{[2
]}

Patel, Chetan B. ^{[2
]}

Bryner, Benjamin S. ^{[1
]}

Schroder, Jacob N. ^{[1
]}

机构：

[1] Duke Univ, Dept Surg, Div Cardiovasc & Thorac Surg, Med Ctr, Durham, NC 27710 USA

[2] Duke Univ, Dept Med, Div Cardiol, Med Ctr, Durham, NC 27710 USA

来源：

JOURNAL OF CARDIAC FAILURE | 2021年 / 27卷 / 12期

关键词：

D O I：

10.1016/j.cardfail.2021.07.018

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The recently concluded prospective Portable Organ Care System (OCS) I lead trial to Evaluate the Safety and Effectiveness of The Portable Organ Care System Heart lor Preserving and Assessing Expanded Criteria Donor Hearts for Transplantation (EXPAND) demonstrated that the use of ex vivo perfusion for expanded-criteria hearts may he a viable method for increasing the use of donor hearts. We sought to estimate the potential impact of ex vivo expanded-criteria heart perfusion on the donor pool in the United States by using a large national transplant registry. Alter applying the inclusion criteria of EXPAND. 8637 potentially eligible donors were identified in the U.S. between January I. 2015. and June 30. 2019. representing a substantial potential increase in the donor pool.

引用

页码：1462 / 1465

页数：4

共 5 条

[1] New Strategies to Expand and Optimize Heart Donor Pool: Ex Vivo Heart Perfusion and Donation After Circulatory Death: A Review of Current Research and Future Trends [J].

Beuth, Jodie ;

Falter, Florian ;

Ribeiro, Roberto Vanin Pinto ;

Badiwala, Mitesh ;

Meineri, Massimiliano .

ANESTHESIA AND ANALGESIA, 2019, 128 (03) :406-413

[2] Current status and future aspects of ex vivo allograft perfusion for heart transplantation [J].

Fukushima, Norihide .

JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2017, 36 (03) :247-249

[3]

Hart A, 2020, AM J TRANSPLANT, V20, DOI [10.1111/ajt.15673, 10.1111/ajt.15672, 10.1111/ajt.15676]

[4] Successful Utilization of Extended Criteria Donor (ECD) Hearts for Transplantation - Results of the OCS™ Heart EXPAND Trial to Evaluate the Effectiveness and Safety of the OCS Heart System to Preserve and Assess ECD Hearts for Transplantation [J].

Schroder, J. N. ;

D'Alessandro, D. ;

Esmailian, F. ;

Boeve, T. ;

Tang, P. ;

Liao, K. ;

Wang, I. ;

Anyanwu, A. ;

Shah, A. ;

Mudy, K. ;

Soltesz, E. ;

Smith, J. W. .

JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2019, 38 (04) :S42-S42

[5]

U.S. Food & Drug Administration, 2021, CIRC SYST DEV PAN ME

← 1 →