Type of Thrombolytic Agent and Rate of Acute Kidney Injury in Patients With Myocardial Infarction

被引：0
作者：
Menzorov, M. V. [1 ]
Shutov, A. M. [1 ]
Serov, V. A. [1 ]
Saenko, Y. V. [1 ]
Grishenkin, I. Y. [1 ]
机构：
[1] Ulyanovsk State Univ, Dept Internal Med, Ulyanovsk 432063, Russia
来源：
KARDIOLOGIYA | 2015年 / 55卷 / 02期
关键词：
ST-elevation myocardial infarction; acute kidney injury; streptokinase; alteplase; arterial hypotension; CONTRAST-INDUCED NEPHROPATHY; SHORT-TERM OUTCOMES; DISEASE;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Aim of this study was to assess incidence and severity of acute kidney injury (AKI) in patients with ST-elevation (STE) myocardial infarction (MI) after thrombolytic therapy with alteplase or streptokinase. Among 292 included patients (227 men, 65 women, mean age 58 +/- 11 years) 170 received streptokinase, 122 - alteplase. Coronary angiography in acute stage of MI was an exclusion criterion. Thrombolysis was effective in 213 (73%) patients. There was no statistically significant difference in effectiveness of thrombolysis among streptokinase or alteplase treated patients. Incidence of AKI in patients with STEMI was 25%. Both incidence and severity of AKI were higher in streptokinase treated patients. Only stage II-III AKI was significantly associated with higher in-hospital mortality.
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页码：16 / 20
页数：5
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