A neural network algorithm for detection of GI angiectasia during small-bowel capsule endoscopy

被引:150
作者
Leenhardt, Romain [1 ]
Vasseur, Pauline [2 ]
Li, Cynthia [1 ,3 ]
Saurin, Jean Christophe [4 ]
Rahmi, Gabriel [5 ]
Cholet, Franck [6 ]
Becq, Aymeric [1 ]
Marteau, Philippe [1 ]
Histace, Aymeric [2 ]
Dray, Xavier [1 ,2 ]
机构
[1] Sorbonne Univ, St Antoine Hosp, AP HP, Dept Hepatogastroenterol, Paris, France
[2] Univ Cergy Pontoise, CNRS, ETIS, ENSEA, Cergy Pontoise, France
[3] Drexel Univ, Coll Arts & Sci, Philadelphia, PA 19104 USA
[4] Hop Edouard Herriot, Dept Endoscopy & Gastroenterol, Pavillon L, Lyon, France
[5] Georges Pompidou European Hosp, AP HP, Dept Gastroenterol & Endoscopy, Paris, France
[6] Univ Hosp, Digest Endoscopy Unit, Brest, France
关键词
DIAGNOSIS;
D O I
10.1016/j.gie.2018.06.036
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background and Aims: GI angiectasia (GIA) is the most common small-bowel (SB) vascular lesion, with an inherent risk of bleeding. SB capsule endoscopy (SB-CE) is the currently accepted diagnostic procedure. The aim of this study was to develop a computer-assisted diagnosis tool for the detection of GIA. Methods: Deidentified SB-CE still frames featuring annotated typical GIA and normal control still frames were selected from a database. A semantic segmentation images approach associated with a convolutional neural network (CNN) was used for deep-feature extractions and classification. Two datasets of still frames were created and used for machine learning and for algorithm testing. Results: The GIA detection algorithm yielded a sensitivity of 100%, a specificity of 96%, a positive predictive value of 96%, and a negative predictive value of 100%. Reproducibility was optimal. The reading process for an entire SB-CE video would take 39 minutes. Conclusions: The developed CNN-based algorithm had high diagnostic performances, allowing detection of GIA in SB-CE still frames. This study paves the way for future automated CNN-based SB-CE reading softwares.
引用
收藏
页码:189 / 194
页数:6
相关论文
共 12 条
[1]   Hemorrhagic angiodysplasia of the digestive tract: pathogenesis, diagnosis, and management [J].
Becq, Aymeric ;
Rahmi, Gabriel ;
Perrod, Guillaume ;
Cellier, Christophe .
GASTROINTESTINAL ENDOSCOPY, 2017, 86 (05) :792-806
[2]   Accurate Classification of Diminutive Colorectal Polyps Using Computer-Aided Analysis [J].
Chen, Peng-Jen ;
Lin, Meng-Chiung ;
Lai, Mei-Ju ;
Lin, Jung-Chun ;
Lu, Henry Horng-Shing ;
Tseng, Vincent S. .
GASTROENTEROLOGY, 2018, 154 (03) :568-575
[3]   Software for enhanced video capsule endoscopy: challenges for essential progress [J].
Iakovidis, Dimitris K. ;
Koulaouzidis, Anastasios .
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2015, 12 (03) :172-186
[4]   Optimizing lesion detection in small-bowel capsule endoscopy: from present problems to future solutions [J].
Koulaouzidis, Anastasios ;
Iakovidis, Dimitris K. ;
Karargyris, Alexandros ;
Plevris, John N. .
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 2015, 9 (02) :217-235
[5]  
Leenhardt R, 2018, GASTROINTEST ENDOSC, V87, pAB149
[6]   Capsule endoscopy of the small bowel [J].
McAlindon, Mark E. ;
Ching, Hey-Long ;
Yung, Diana ;
Sidhu, Reena ;
Koulaouzidis, Anastasios .
ANNALS OF TRANSLATIONAL MEDICINE, 2016, 4 (19)
[7]  
Noya F, 2017, IEEE ENG MED BIO, P3158, DOI 10.1109/EMBC.2017.8037527
[8]   Bleeding Detection in Wireless Capsule Endoscopy Based on Probabilistic Neural Network [J].
Pan, Guobing ;
Yan, Guozheng ;
Qiu, Xiangling ;
Cui, Jiehao .
JOURNAL OF MEDICAL SYSTEMS, 2011, 35 (06) :1477-1484
[9]   Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline [J].
Pennazio, Marco ;
Spada, Cristiano ;
Eliakim, Rami ;
Keuchel, Martin ;
May, Andrea ;
Mulder, Chris J. ;
Rondonotti, Emanuele ;
Adler, Samuel N. ;
Albert, Joerg ;
Baltes, Peter ;
Barbaro, Federico ;
Cellier, Christophe ;
Charton, Jean Pierre ;
Delvaux, Michel ;
Despott, Edward J. ;
Domagk, Dirk ;
Klein, Amir ;
McAlindon, Mark ;
Rosa, Bruno ;
Rowse, Georgina ;
Sanders, David S. ;
Saurin, Jean Christophe ;
Sidhu, Reena ;
Dumonceau, Jean-Marc ;
Hassan, Cesare ;
Gralnek, Ian M. .
ENDOSCOPY, 2015, 47 (04) :352-376
[10]   Multicenter prospective evaluation of the express view reading mode for small-bowel capsule endoscopy studies [J].
Saurin, Jean-Christophe ;
Jacob, Philippe ;
Heyries, Laurent ;
Pesanti, Christian ;
Cholet, Franck ;
Fassler, Isaac ;
Boulant, James ;
Bramli, Slim ;
De Leusse, Antoin ;
Rahmi, Gabriel .
ENDOSCOPY INTERNATIONAL OPEN, 2018, 6 (05) :E616-E621