Bone sarcoma;
fibula;
iliac crest;
medial femoral condyle;
limb-sparing procedure;
vascularized bone graft;
vascularized bone graft reconstruction;
LIMB-SALVAGE;
EXTRACORPOREAL IRRADIATION;
FIBULAR GRAFTS;
SKELETAL DEFECTS;
SURGERY;
HYPERTROPHY;
ALLOGRAFT;
REIMPLANTATION;
REPLACEMENT;
MANAGEMENT;
D O I:
10.21873/anticanres.15316
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Background/Aim: Limb-sparing procedures are frequently applied to improve patient outcomes. The use of vascularized bone grafts is associated with significant improvements in oncologic safety and functional satisfaction. This study highlights the clinical outcomes following tumor resection combined with vascularized bone graft reconstructions. Patients and Methods: Twenty-five free vascularized bone grafts (17 fibulas, 5 iliac crests, 3 medial femoral condyles) were assessed with respect to consolidation and hypertrophy, functional and oncologic outcomes, and local complications. Results: The rate of healing of fibular grafts after a median of 5 months was 86%. The rate of achieved unions of iliac crest grafts after a median of 5 months was 80%. In medial femoral condyle bone grafts, union occurred after a median of 4 months. Significant hypertrophy was observed in 13 patients. We identified six complications with highest rates in the fibulagroup. Despite the high complications, functional results were highly satisfactory. Conclusion: Vascularized bone grafts represent a reconstructive approach, maintaining long-term functionality and cosmetic satisfaction without compromising tumor recurrence outcomes.
机构:
Chinese Univ Hong Kong, Prince Wales Hosp, Orthopaed Oncol, Hong Kong, Peoples R ChinaChinese Univ Hong Kong, Prince Wales Hosp, Orthopaed Oncol, Hong Kong, Peoples R China
Wong, Kwok-Chuen
Niu, Xiaohui
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机构:
Peking Univ, Beijing Ji Shui Tan Hosp, Dept Orthopaed Oncol Surg, Beijing 100035, Peoples R ChinaChinese Univ Hong Kong, Prince Wales Hosp, Orthopaed Oncol, Hong Kong, Peoples R China
Niu, Xiaohui
Xu, Hairong
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机构:
Peking Univ, Beijing Ji Shui Tan Hosp, Dept Orthopaed Oncol Surg, Beijing 100035, Peoples R ChinaChinese Univ Hong Kong, Prince Wales Hosp, Orthopaed Oncol, Hong Kong, Peoples R China
Xu, Hairong
Li, Yuan
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机构:
Peking Univ, Beijing Ji Shui Tan Hosp, Dept Orthopaed Oncol Surg, Beijing 100035, Peoples R ChinaChinese Univ Hong Kong, Prince Wales Hosp, Orthopaed Oncol, Hong Kong, Peoples R China
Li, Yuan
Kumta, Shekhar Madhukar
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机构:
Chinese Univ Hong Kong, Prince Wales Hosp, Orthopaed Oncol, Hong Kong, Peoples R ChinaChinese Univ Hong Kong, Prince Wales Hosp, Orthopaed Oncol, Hong Kong, Peoples R China