Iridium-Catalyzed 1,3-Dipolar Cycloadditions

被引：4

作者：

Carmona, Daniel ^{[1
]}

Oro, Luis A. ^{[1
]}

机构：

[1] Univ Zaragoza, Inst Ciencia Mat Aragon, CSIC, E-50009 Zaragoza, Spain

来源：

IRIDIUM CATALYSIS | 2011年 / 34卷

关键词：

1,3-Dipolar cycloadditions; Enals; Iridium catalysts; Methacrylonitrile; Nitrones; LEWIS-ACID; ALPHA; BETA-UNSATURATED ALDEHYDES; NITRONE CYCLOADDITION; RUTHENIUM COMPLEXES; RHODIUM; REACTIVITY; ALKENES; REGIOSELECTIVITY; SUBSTITUENT; MECHANISM;

D O I：

10.1007/978-3-642-15334-1_8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

1,3-Dipolar cycloaddition reactions (DCR) are atom-economic processes that permit the construction of heterocycles. Their enantioselective versions allow for the creation of up to four adjacent chiral centers in a concerted fashion. In particular, well-defined half-sandwich iridium (III) catalysts have been applied to the DCR between enals or methacrylonitrile with nitrones. Excellent yield and stereoselectivities have been achieved. Support for mechanistic proposals stems from the isolation and characterization of the true catalysts.

引用

页码：209 / 229

页数：21

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