Autoimmune disease - Skin deep but complex

被引:13
作者
Baumgarth, Nicole [1 ]
Bevins, Charles L.
机构
[1] Univ Calif Davis, Ctr Comparat Med, Sch Vet Med, Dept Pathol Microbiol & Immunol, Davis, CA 95616 USA
[2] Univ Calif Davis, Immunol Grad Grp, Davis, CA 95616 USA
[3] Univ Calif Davis, Sch Med, Dept Microbiol & Immunol, Davis, CA 95616 USA
关键词
D O I
10.1038/nature05893
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The antimicrobial peptide LL37 is essential for normal immune responses to infection or tissue injury. But in the autoimmune skin disorder psoriasis, LL37 propagates disease by forming complexes with host DNA.
引用
收藏
页码:551 / +
页数:2
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