The role of environmental factors and molecular genetics diagnosis in treatment of breast cancer in Iran, Qom (2019-2020)

Cancer is one of the leading causes of death and disability worldwide, especially in developing countries. Development is considered. In most cases, cancer is not because of the person's innate biology, but because of the environment in which the person lives are created. In this study, the available evidence on the role of environmental factors and how they affect the incidence of cancer Has been reviewed. BRCA1 and BRCA2 are the two most important high-risk genes for hereditary breast cancer. A significant proportion of familial breast cancer is caused by mutations in the CHEK2 gene. Other gene susceptibility alleles are also uncommon causes of breast cancer. More than 1000 mutations in BRCA1 and BRCA2 have been found, and molecular techniques for detecting mutations in these genes are now well established. Mutations in BRCA1 and BRCA2 generate genomic instability, which leads to changes in other important genes, such as tumor suppressor genes and/or oncogenes. In the near future, there is the possibility of personalizing treatment plans for individual women. The discovery of miRNAs as gene expression regulators establishes them as a novel candidate for diagnostic and prognostic markers, as well as therapeutic targets. Information related to crime victims Cancer patients during the years 2019 to 2020 in Iran in Qom city. It was recorded that it has been collected and has been analyzed and analyzed. In this review the PARS codes. They are used as diagnostic codes for breast cancer are ICD of 10 C50. The number of registered breast cancers during these three years was 399. The number of registered breast cancers during these three years has been 399.