Synthesis and antibacterial activity of 2,4,6-tri substituted s-triazines

被引：98
作者：
Srinivas, K
Srinivas, U
Rao, VJ
Bhanuprakash, K
Kishore, KH
Murty, USN
机构：
[1] Indian Inst Chem Technol, Div Organ Chem 2, Hyderabad 500007, Andhra Pradesh, India
[2] Indian Inst Chem Technol, Inorgan & Phys Chem Div, Hyderabad 500007, Andhra Pradesh, India
[3] Indian Inst Chem Technol, Div Biol, Hyderabad 500007, Andhra Pradesh, India
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2005年 / 15卷 / 04期
关键词：
s-triazines; synthesis; antibacterial activity; antifungal activity;
D O I：
10.1016/j.bmcl.2004.12.020
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Various 2,4,6-tri substituted s-triazines were synthesized and screened for antibacterial activity against Gram-positive and Gram-negative organisms. These s-triazine derivatives displayed high in vitro antibacterial activities comparable to penicillin and streptomycin against tested microorganisms. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1121 / 1123
页数：3
相关论文
共 24 条
[1]  
BARRETTA GU, 1998, J ORG CHEM, V63, P9197
[2]   Synthesis, structural characterization and antitumor activity of novel 2,4-diamino-1,3,5-triazine derivatives [J].
Brzozowski, Z ;
Saczewski, F ;
Gdaniec, M .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2000, 35 (12) :1053-1064
[3]  
Dhainaunt A, 1996, J MED CHEM, V39, P4354
[4]   Synthesis and characterization of a novel functional monomer containing two allylphenoxy groups and one S-triazine ring and the properties of its copolymer with 4,4′-bismaleimidodiphenylmethane (BMDPM) [J].
Fang, Q ;
Ding, XM ;
Wu, XY ;
Jiang, LX .
POLYMER, 2001, 42 (18) :7595-7602
[5]   Synthesis of variously 9,9-dialkylated octahydropyrimido [3,4-a]-s-triazines with potential antifungal activity [J].
Ghaib, A ;
Ménager, S ;
Vérité, P ;
Lafont, O .
FARMACO, 2002, 57 (02) :109-116
[6]   A new series of estrogen receptor modulators that display selectivity for estrogen receptor β [J].
Henke, BR ;
Consler, TG ;
Go, N ;
Hale, RL ;
Hohman, DR ;
Jones, SA ;
Lu, AT ;
Moore, LB ;
Moore, JT ;
Orband-Miller, LA ;
Robinett, RG ;
Shearin, J ;
Spearing, PK ;
Stewart, EL ;
Turnbull, PS ;
Weaver, SL ;
Williams, SP ;
Wisely, GB ;
Lambert, MH .
JOURNAL OF MEDICINAL CHEMISTRY, 2002, 45 (25) :5492-5505
[7]   Antibacterial single-bead screening [J].
Lebreton, S ;
Newcombe, N ;
Bradley, M .
TETRAHEDRON, 2003, 59 (51) :10213-10222
[8]  
LESPAGNOL A, 1975, CHIMIE MEDICAMENTS T, V3, P313
[9]   Design, synthesis, and structure-activity relationship studies of ATP analogues as DNA gyrase inhibitors [J].
Lübbers, T ;
Angehrn, P ;
Gmünder, H ;
Herzig, S ;
Kulhanek, J .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2000, 10 (08) :821-826
[10]  
MAYUMI O, 1996, CANCER RES, V56, P1512
123