Synthesis of chiral building blocks for cephalostatin analogues

被引：4

作者：

Yunus, U

Iqbal, R

Winterfeldt, E

机构：

[1] Allama Iqbal Open Univ, Dept Chem, Islamabad, Pakistan

[2] Quaid I Azam Univ, Dept Chem, Islamabad, Pakistan

[3] Univ Hannover, Inst Organ Chem, Schneiderberg, Germany

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2005年 / 42卷 / 06期

关键词：

D O I：

10.1002/jhet.5570420607

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The present paper describes the synthesis of 5-azido-6-ketones (14) and 6-hydroxy-5-ketone (20) from Hajos Wiechert ketone as chiral building blocks for cephalostatin analogues. The synthesis of symmetric cephalostatin analogue from 6-hydroxy-5-ketone has also been reported. The characterization of the each synthesized compounds was carried out by IR, H-1-NMR, C-13-NMR and High resolution Mass Spectrometry.

引用

页码：1079 / 1084

页数：6

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