Flavonoids, anti-inflammatory activity and cytotoxicity of Macfadyena unguis-cati L.

被引：0

作者：

Aboutabl, E. A. ^{[1
]}

Hashem, F. A. ^{[2
]}

Sleem, A. A. ^{[3
]}

Maamoon, A. A. ^{[2
]}

机构：

[1] Cairo Univ, Fac Pharm, Dept Pharmacognosy, Cairo, Egypt

[2] Natl Res Ctr, Dept Pharmacognosy, Cairo, Egypt

[3] Natl Res Ctr, Dept Pharmacol, Cairo, Egypt

来源：

AFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINES | 2008年 / 5卷 / 01期

关键词：

Macfadyena unguis-cati L; Bignoniaceae; flavonoids; anti-inflammatory; cytotoxicity;

D O I：

暂无

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Ethyl acetate and ethanol extracts of unflowering aerial part of Macfadyena unguis-cati L.( Fam. Bignoniaceae) were found to be rich in phenolic compounds. From ethyl acetate extract, six flavonoids were identified, 8, methoxy, acacetin, 7-O glucoside; 6, methoxy apigenin 7-O glucoside; 4'-O methyl scutellarin, 6-O apiosyl galactoside; acacetin, 7-O glucosyl, 8-C rhamnosyl, 3-O-alpha arabinofuranoside; 4'-methyl, 6-methoxy kaempferol, 7-O, 8-C diglucoside and vicenin II were isolated, while 6, methoxy, acacetin 7-O glucoside; and quercitrin were isolated from ethanol extract. These compounds were characterized and identified by their physicochemical and spectral data. The crude ethanol extract exhibited significant anti-inflammatory activity (80.47%) and moderate cytotoxic activity against lung cell line.

引用

页码：18 / 26

页数：9

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