Cardiovascular autonomic neuropathy: A silent killer with long reach

被引：30

作者：

Ang, Lynn ^{[1
]}

Dillon, Brendan ^{[2
]}

Mizokami-Stout, Kara ^{[1
]}

Pop-Busui, Rodica ^{[1
]}

机构：

[1] Univ Michigan, Div Metab Endocrinol & Diabet, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Med Sch, Ann Arbor, MI USA

来源：

AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL | 2020年 / 225卷

关键词：

Cardiovascular autonomic neuropathy; Cardiovascular autonomic dysfunction; Cardiovascular disease; Diabetes mellitus; HEART-RATE-VARIABILITY; NOCTURNAL BLOOD-PRESSURE; TYPE-1; DIABETES-MELLITUS; IMPAIRED GLUCOSE-TOLERANCE; NERVOUS-SYSTEM FUNCTION; OXIDATIVE STRESS; SPECTRAL-ANALYSIS; RISK-FACTORS; GLYCEMIC VARIABILITY; STANDARD-TESTS;

D O I：

10.1016/j.autneu.2020.102646

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Cardiovascular autonomic neuropathy (CAN) is a common and deadly complication of diabetes mellitus, which is frequently overlooked in clinical practice due to its characteristic subtle presentation earlier in disease. Yet, timely detection of CAN may help implementation of tailored interventions to prevent its progression and mitigate the risk of associated complications, including cardiovascular disease (CVD), cardiac arrhythmias, myocardial dysfunction leading to congestive heart failure and all-cause mortality. This review highlights current CAN epidemiology trends, novel mechanisms linking CAN with other diabetes complications and current recommendations for diagnosis and management of the disease in the clinical setting.

引用

页数：9

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