Spectrum-effect relationship study between HPLC fingerprints and antioxidant activity of Sabia parviflora

被引：35

作者：

Chen, Yinrui ^{[1
]}

Pan, Guoji ^{[1
]}

Xu, Wenfen ^{[1
]}

Sun, Qingwen ^{[1
]}

Wang, Bo ^{[1
]}

Zhang, Ye ^{[1
]}

Yang, Tianjin ^{[1
]}

机构：

[1] Guizhou Univ Tradit Chinese Med, Guiyang 550025, Peoples R China

来源：

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 2020年 / 1140卷

基金：

中国国家自然科学基金;

关键词：

Sabia parviflora; Anti-oxidation; HPLC fingerprints; Spectrum-effect relationship; Flavonoid; PHENOLIC-COMPOUNDS; CLASSIFICATION; ACCUMULATION; MECHANISMS;

D O I：

10.1016/j.jchromb.2020.121970

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Nowadays, the increased prevalence of sub-health significantly affects human health worldwide. Suppressed sub-healthy by dietotherapy/herbal remedy which showed excellent safety profile, low cost and effectiveness, is an effective way. In this research, the fingerprint and antioxidant activity of Sabia parviflora were obtained by HPLC instrument and DPPH, ABTS, FRAP heatmap assays. And the antioxidant active substances were selected by spectrum-effect relationship. The results showed that significant differences in chemical compositions of samples from different sources, and EW, EE extracts had strong antioxidant activity. The antioxidant activity of Sabia parviflora was mainly determined by the complex interaction of various flavonoids (promoting, competing or antagonizing). These findings revealed that the abundant flavonoids in Sabia parviflora had significant antioxidant activity and could be potential antioxidants. With therapeutic potential for sub-health, this special tea might provide dietotherapy/herbal to remedy sub-healthy population.

引用

页数：12

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