Impact of obesity on cervical ossification of the posterior longitudinal ligament: a nationwide prospective study

被引：4

作者：

Mori, Kanji ^{[1
,31
]}

Yoshii, Toshitaka ^{[2
,31
]}

Egawa, Satoru ^{[2
,31
]}

Sakai, Kenichiro ^{[3
,31
]}

Kusano, Kazuo ^{[4
,31
]}

Tsutsui, Shunji ^{[5
,31
]}

Hirai, Takashi ^{[2
,31
]}

Matsukura, Yu ^{[2
,31
]}

Wada, Kanichiro ^{[6
,31
]}

Katsumi, Keiichi ^{[7
,31
]}

Koda, Masao ^{[8
,31
]}

Kimura, Atsushi ^{[9
,31
]}

Furuya, Takeo ^{[10
,31
]}

Maki, Satoshi ^{[10
,31
]}

Nagoshi, Narihito ^{[11
,31
]}

Nishida, Norihiro ^{[12
,31
]}

Nagamoto, Yukitaka ^{[13
,31
]}

Oshima, Yasushi ^{[14
,31
]}

Ando, Kei ^{[15
,31
]}

Nakashima, Hiroaki ^{[15
,31
]}

Takahata, Masahiko ^{[16
,17
,31
]}

Nakajima, Hideaki ^{[18
,31
]}

Murata, Kazuma ^{[19
,31
]}

Miyagi, Masayuki ^{[20
,31
]}

Kaito, Takashi ^{[21
,31
]}

Yamada, Kei ^{[22
,31
]}

Banno, Tomohiro ^{[23
,31
]}

Kato, Satoshi ^{[24
,31
]}

Ohba, Tetsuro ^{[25
,31
]}

Inami, Satoshi ^{[26
,31
]}

Fujibayashi, Shunsuke ^{[27
,31
]}

Katoh, Hiroyuki ^{[28
,31
]}

Kanno, Haruo ^{[29
,31
]}

Taneichi, Hiroshi ^{[26
,31
]}

Imagama, Shiro ^{[15
,31
]}

Kawaguchi, Yoshiharu ^{[30
,31
]}

Takeshita, Katsushi ^{[9
,31
]}

Matsumoto, Morio ^{[11
,31
]}

Yamazaki, Masashi ^{[8
,31
]}

Okawa, Atsushi ^{[2
,31
]}

机构：

[1] Shiga Univ Med Sci, Dept Orthopaed Surg, Seta Tsukinowa Cho, Otsu, Shiga 5202192, Japan

[2] Tokyo Med & Dent Univ, Dept Orthoped Surg, Bunkyo Ward, 1-5-45 Yushima, Tokyo 1138519, Japan

[3] Saiseikai Kawaguchi Gen Hosp, Dept Orthoped Surg, 5-11-5 Nishikawaguchi, Kawaguchi, Saitama 3328558, Japan

[4] Kudanzaka Hosp, Dept Orthoped Surg, Chiyoda Ku, 1-6-12 Kudanminami, Tokyo 1020074, Japan

[5] Wakayama Med Univ, Dept Orthopaed Surg, 811-1 Kimiidera, Wakayama 6418510, Japan

[6] Hirosaki Univ, Grad Sch Med, Dept Orthoped Surg, 5 Zaifu Cho, Hirosaki, Aomori 0368562, Japan

[7] Niigata Univ, Med & Dent Gen Hosp, Dept Orthoped Surg, Chuo Ward, 1-754 Asahimachidori, Niigata, Niigata 9518520, Japan

[8] Univ Tsukuba, Fac Med, Dept Orthoped Surg, 1-1-1 Tennodai, Tsukuba, Ibaraki 3058575, Japan

[9] Jichi Med Univ, Dept Orthoped, 3311-1 Yakushiji, Shimotsuke, Tochigi 3290498, Japan

[10] Chiba Univ, Grad Sch Med, Dept Orthoped Surg, Chuo Ward, 1-8-1 Inohana, Chiba, Chiba 2600856, Japan

[11] Keio Univ, Sch Med, Dept Orthopaed Surg, Shinjuku Ward, 35 Shinanomachi, Tokyo 1608582, Japan

[12] Yamaguchi Univ, Grad Sch, Dept Orthoped Surg, Med, 1-1-1 Minami Kogushi, Ube, Yamaguchi 7558505, Japan

[13] Osaka Rosai Hosp, Dept Orthoped Surg, 1179-3 Nagasonecho, Sakai, Osaka 5918025, Japan

[14] Univ Tokyo, Fac Med, Dept Orthopaed Surg, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1130033, Japan

[15] Nagoya Univ, Grad Sch Med, Dept Orthoped Surg, Showa Ward, 65 Tsurumaicho, Nagoya, Aichi 4668550, Japan

[16] Hokkaido Univ, Fac Med, Dept Orthopaed Surg, Kita 15,Nishi 7, Sapporo, Hokkaido 0608638, Japan

[17] Hokkaido Univ, Grad Sch Med, Kita 15,Nishi 7, Sapporo, Hokkaido 0608638, Japan

[18] Univ Fukui, Fac Med Sci, Dept Orthopaed & Rehabil Med, 23-3 Matsuoka Shimoaizuki, Eiheiji, Fukui 9101193, Japan

[19] Tokyo Med Univ, Dept Orthoped Surg, Shinjuku Ku, 6-7-1 Nishishinjuku, Tokyo 1600023, Japan

[20] Kitasato Univ, Sch Med, Dept Orthoped Surg, Minami Ku, 1-15-1 Kitazato, Sagamihara, Kanagawa 2520375, Japan

[21] Osaka Univ, Grad Sch Med, Dept Orthoped Surg, 2-2 Yamadaoka, Suita, Osaka 5650871, Japan

[22] Kurume Univ, Sch Med, Dept Orthopaed Surg, 67 Asahi Machi, Kurume, Fukuoka 8300011, Japan

[23] Hamamatsu Univ, Sch Med, Dept Orthoped Surg, 1-20-1 Handayama, Hamamatsu, Shizuoka 4313125, Japan

[24] Kanazawa Univ, Grad Sch Med Sci, Dept Orthopaed Surg, 13-1 Takara Machi, Kanazawa, Ishikawa 9208641, Japan

[25] Univ Yamanashi, Dept Orthoped Surg, Chuo Ward, 1110 Shimokato, Yamanashi 4093898, Japan

[26] Dokkyo Med Univ, Sch Med, Dept Orthopaed Surg, 880 Kitakobayashi, Mibu, Tochigi 3210293, Japan

[27] Kyoto Univ, Grad Sch Med, Dept Orthopaed Surg, Sakyo Ku, 54 Kawahara Cho, Kyoto 6068507, Japan

[28] Tokai Univ, Sch Med, Dept Orthoped Surg, Surg Sci, 143 Shimokasuya, Isehara, Kanagawa 2591193, Japan

[29] Tohoku Univ, Sch Med, Dept Orthopaed Surg, Aoba Ward, 1-1 Seiryomachi, Sendai, Miyagi 9808574, Japan

[30] Univ Toyama, Fac Med, Dept Orthoped Surg, 2630 Sugitani, Toyama, Toyama 9300194, Japan

[31] Japanese Multictr Res Org Ossificat Spinal Ligame, Tokyo, Japan

来源：

SCIENTIFIC REPORTS | 2022年 / 12卷 / 01期

关键词：

SURGICAL SITE INFECTION; COMPLICATIONS; ASSOCIATION; MANAGEMENT; SURGERY;

D O I：

10.1038/s41598-022-12625-3

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Positive association between ossification of the posterior longitudinal ligament of the spine (OPLL) and obesity is widely recognized; however, few studies focused on the effects of obesity on treatment of cervical OPLL. The effects of obesity on surgical treatment of cervical OPLL were investigated by a Japanese nationwide, prospective study. Overall, 478 patients with cervical myelopathy due to OPLL were prospectively enrolled. To clarify the effects of obesity on the surgical treatment for cervical OPLL, patients were stratified into two groups, non-obese (< BMI 30.0 kg/m(2)) and obese (>= BMI 30.0 kg/m(2)) groups. The mean age of the obese group was significantly younger than that of non-obese group. There were no significant differences between the two groups in other demographic information, medical history, and clinical and radiographical findings. Alternatively, the obese group had a significantly higher rate of surgical site infection (SSI) than that of non-obese group. Approach-specific analyses revealed that the SSI was significantly higher in the obese group than in the non-obese group. A logistic regression analysis revealed that age, BMI, and duration of symptoms were significant factors affecting the postoperative minimum clinically important difference success. The result of this study provides useful information for future cervical OPLL treatment.

引用

页数：10

共 33 条

[1] Cervical Ossification of the Posterior Longitudinal Ligament: A Computed Tomography-Based Epidemiological Study of 2917 Patients [J].