Laboratory-size x-ray microscope using Wolter mirror optics and an electron-impact x-ray source

被引：8

作者：

Ohba, Akira ^{[1
]}

Nakano, Tomoyasu ^{[1
]}

Onoda, Shinobu ^{[1
]}

Mochizuki, Takahiro ^{[1
]}

Nakamoto, Katsuhiro ^{[1
]}

Hotaka, Hisaya ^{[1
]}

机构：

[1] Hamamatsu Photon KK, Hamakita Ku, 5000 Hirakuchi, Hamamatsu, Shizuoka 4348601, Japan

来源：

REVIEW OF SCIENTIFIC INSTRUMENTS | 2021年 / 92卷 / 09期

关键词：

TRANSMISSION; TOMOGRAPHY; FIELD; WHOLE;

D O I：

10.1063/5.0059906

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

We developed a laboratory-size three-dimensional water-window x-ray microscope using condenser and objective grazing incidence Wolter type I mirrors, an electron-impact-type x-ray source, and a back-illuminated CCD. The imaging system was improved for practical applications in life science research fields. Using a new objective mirror with reduced figure errors, a resolution limit of 3.1 line pairs/mu m was achieved for two-dimensional transmission images and sub-micrometer-scale three-dimensional structures were resolved. Incorporating a cryogenic stage into the x-ray microscope, we observed biological samples embedded in ice to evaluate the usefulness of observation in the water-window region and multi-energy observation was demonstrated using an x-ray source with multiple x-ray tubes. Published under an exclusive license by AIP Publishing.

引用

页数：8

共 22 条

[1] Laboratory-Based Cryogenic Soft X-Ray Tomography with Correlative Cryo-Light and Electron Microscopy [J].

Carlson, David B. ;

Gelb, Jeff ;

Palshin, Vadim ;

Evans, James E. .

MICROSCOPY AND MICROANALYSIS, 2013, 19 (01) :22-29

[2] Single-shot achromatic imaging for broadband soft x-ray pulses [J].

Egawa, Satoru ;

Motoyama, Hiroto ;

Iwasaki, Atsushi ;

Yamaguchi, Gota ;

Kume, Takehiro ;

Yamanouchi, Kaoru ;

Mimura, Hidekazu .

OPTICS LETTERS, 2020, 45 (02) :515-518

[3] High throughput and wide field of view EUV microscope for blur-free one-shot imaging of living organisms [J].

Ejima, Takeo ;

Ishida, Fumihiko ;

Murata, Hiromichi ;

Toyoda, Mitsunori ;

Harada, Tetsuo ;

Tsuru, Toshihide ;

Hatano, Tadashi ;

Yanagihara, Mihiro ;

Yamamoto, Masaki ;

Mizutani, Haruo .

OPTICS EXPRESS, 2010, 18 (07) :7203-7209

[4] Laboratory cryo x-ray microscopy for 3D cell imaging [J].

Fogelqvist, Emelie ;

Kordel, Mikael ;

Carannante, Valentina ;

Onfelt, Bjorn ;

Hertz, Hans M. .

SCIENTIFIC REPORTS, 2017, 7

[5] Cryo transmission X-ray imaging of the malaria parasite, P. falciparum [J].

Hanssen, Eric ;

Knoechel, Christian ;

Klonis, Nectarios ;

Abu-Bakar, Nurhidanatasha ;

Deed, Samantha ;

LeGros, Mark ;

Larabell, Carolyn ;

Tilley, Leann .

JOURNAL OF STRUCTURAL BIOLOGY, 2011, 173 (01) :161-168

[6] X-RAY INTERACTIONS - PHOTOABSORPTION, SCATTERING, TRANSMISSION, AND REFLECTION AT E=50-30,000 EV, Z=1-92 [J].

HENKE, BL ;

GULLIKSON, EM ;

DAVIS, JC .

ATOMIC DATA AND NUCLEAR DATA TABLES, 1993, 54 (02) :181-342

[7] Laboratory-scale soft X-ray imaging microtomography using Wolter mirror optics [J].

Hoshino, Masato ;

Aoki, Sadao .

APPLIED PHYSICS EXPRESS, 2008, 1 (06) :0670051-0670053

[8] Quantitative 3D imaging of whole, unstained cells by using X-ray diffraction microscopy [J].

Jiang, Huaidong ;

Song, Changyong ;

Chen, Chien-Chun ;

Xu, Rui ;

Raines, Kevin S. ;

Fahimian, Benjamin P. ;

Lu, Chien-Hung ;

Lee, Ting-Kuo ;

Nakashima, Akio ;

Urano, Jun ;

Ishikawa, Tetsuya ;

Tamanoi, Fuyuhiko ;

Miao, Jianwei .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (25) :11234-11239

[9] Whole-cell phase contrast imaging at the nanoscale using Fresnel Coherent Diffractive Imaging Tomography [J].

Jones, Michael W. M. ;

van Riessen, Grant A. ;

Abbey, Brian ;

Putkunz, Corey T. ;

Junker, Mark D. ;

Balaur, Eugeniu ;

Vine, David J. ;

McNulty, Ian ;

Chen, Bo ;

Arhatari, Benedicta D. ;

Frankland, Sarah ;

Nugent, Keith A. ;

Tilley, Leann ;

Peele, Andrew G. .

SCIENTIFIC REPORTS, 2013, 3

[10] SELF-CALIBRATION OF SEMICONDUCTOR PHOTODIODES IN THE SOFT-X-RAY REGION [J].

KRUMREY, M ;

TEGELER, E .

REVIEW OF SCIENTIFIC INSTRUMENTS, 1992, 63 (01) :797-801

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