Hypoxia and Amino Acid Imaging of High-Grade Glioma: 18F-FAZA PET/CT and 11C-Methionine PET/MRI

被引：3
作者：
Mapelli, Paola [1 ,2 ]
Fallanca, Federico [2 ]
Scifo, Paola [2 ]
Barbera, Maurizio [3 ,4 ]
Castellano, Antonella [1 ,3 ,4 ]
Bettinardi, Valentino [2 ]
Incerti, Elena [2 ]
Gianolli, Luigi [2 ]
Anzalone, Nicoletta [1 ,3 ,4 ]
Picchio, Maria [1 ,2 ]
机构：
[1] Univ Vita Salute San Raffaele, Milan, Italy
[2] IRCCS San Raffaele Sci Inst, Nucl Med Dept, Milan, Italy
[3] IRCCS San Raffaele Sci Inst, Neuroradiol Unit, Milan, Italy
[4] IRCCS San Raffaele Sci Inst, CERMAC, Milan, Italy
来源：
CLINICAL NUCLEAR MEDICINE | 2020年 / 45卷 / 06期
关键词：
F-18-FAZA; C-11-Methionine; PET/MRI; glioma; PET/CT; 18F-FAZA PET/CT; LUNG-CANCER;
D O I：
10.1097/RLU.0000000000003028
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
In the present case, we report the first experience of a patient with high-grade glioma who underwent dual F-18-FAZA PET/CT imaging for intratumoral hypoxia assessment, before treatment, and for therapy monitoring in the suspicious of recurrence, as part of a clinical research protocol. In addition, despite the diagnosis of glioblastoma, the patient at 3 years from diagnosis was alive and underwent C-11-methionine simultaneous PET/MRI for disease monitoring after treatment, showing stability of disease. The multitracer capability of PET in assessing different and complementary metabolic features along with the use of a last-generation scanner as PET/MRI in brain oncology are here enlighten.
引用
收藏
页码：E290 / E293
页数：4
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