Electrochemical Behavior and Voltammetric Determination of Ketamine at Pulse Plating Gold Film Modified Platinum Electrode

被引:9
作者
Zhou, Jing [1 ]
Xu, Ying [1 ]
Wang, Le [1 ]
Liu, Jie [1 ]
Li, Yamin [1 ]
Ye, Baoxian [1 ]
机构
[1] Zhengzhou Univ, Dept Chem, Zhengzhou 450001, Peoples R China
关键词
Gold film; Ketamine; Pulse plating; Voltammetric sensor; URINE;
D O I
10.1002/jccs.201100659
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An ultrastable chemical modified electrode (CME) was fabricated conveniently based on gold film by pulse plating of chloroauric acid on Pt disk electrode. As a novel modifying method of making CME, the CME was characterized by electrochemical impedance spectroscopy (EIS) and used as a voltammetric sensor for Ketamine. This thin gold film modified electrode exhibited excellent electrocatalysis to Ketamine oxidation. Based on this CME, detection of Ketamine by voltammetry was first erected with a fast-response and wide responding linear range. Further experiments demonstrated that this CME has good stability, repeatability and reproducibility. The established method is accurate, reliable, and can be used for the quality control of Ketamine hydrochloride injection.
引用
收藏
页码:879 / 883
页数:5
相关论文
共 17 条
[1]   Drug-selective electrode for ketamine determination in pharmaceutical preparations and electrochemical study of drug with BSA [J].
Alizadeh, N ;
Mehdipour, R .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2002, 30 (03) :725-731
[2]  
Bard AllenJ., 2001, Fundamentals and applications, V2nd
[3]   Generation of gold nanostructures at the surface of platinum electrode by electrodeposition for ECL detection for CE [J].
Cao, Guangming ;
Liu, Qian ;
Huang, Yan ;
Li, Wang ;
Yao, Shouzhuo .
ELECTROPHORESIS, 2010, 31 (06) :1055-1062
[4]   Determination of ketamine and metabolites in urine by liquid chromatography-mass spectrometry [J].
Chen, Chung-Yu ;
Lee, Maw-Rong ;
Cheng, Fu-Chou ;
Wu, Gong-Jhe .
TALANTA, 2007, 72 (03) :1217-1222
[5]  
Gill JR, 2000, J FORENSIC SCI, V45, P655
[6]   Determination of ketamine and amphetamines in hair by LC/MS/MS [J].
Jesus Tabernero, Maria ;
Felli, Maria Linda ;
Maria Bermejo, Ana ;
Chiarotti, Marcello .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2009, 395 (08) :2547-2557
[7]   Determination of amphetamine-type stimulants, ketamine and metabolites in fingernails by gas chromatography-mass spectrometry [J].
Kim, Jin Young ;
Shin, Soon Ho ;
In, Moon Kyo .
FORENSIC SCIENCE INTERNATIONAL, 2010, 194 (1-3) :108-114
[8]   Inhibitory effects of ketamine and halothane on recombinant potassium channels from mammalian brain [J].
Kulkarni, RS ;
Zorn, LJ ;
Anantharam, V ;
Bayley, H ;
Treistman, SN .
ANESTHESIOLOGY, 1996, 84 (04) :900-909
[9]   Determination of chiral pharmaceutical compounds, terbutaline, ketamine and propranolol, by on-line capillary electrophoresis-electrospray ionization mass spectrometry [J].
Lu, WZ ;
Cole, RB .
JOURNAL OF CHROMATOGRAPHY B, 1998, 714 (01) :69-75
[10]   A comparative study of DC and pulse gold electrodeposits [J].
Mohan, S ;
Raj, V .
TRANSACTIONS OF THE INSTITUTE OF METAL FINISHING, 2005, 83 (02) :72-76