Synthesis of fluorinated halonitrobenzenes and halonitrophenols using tetrafluoroethylene and buta-1,3-dienes as starting building blocks

被引：1
作者：
Volchkov, N. V. [1 ]
Lipkind, M. B. [1 ]
Nefedov, O. M. [1 ]
机构：
[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia
来源：
RUSSIAN CHEMICAL BULLETIN | 2021年 / 70卷 / 11期
关键词：
tetrafluoroethylene; buta-1; 3-diene; cycloaddition; tetrafluorocyclohexenes; halogenation; dehydrohalogenation; 1; 2-difluorobenzene; 1-chloro-2; 3-difluorobenzene; nitration; chlorodifluoronitrobenzenes; 3; 4-difluoronitrobenzenes; 2; 4-trifluoronitrobenzene; 3-difluoro-6-nitrophenol; chlorofluoronitrophenols; AROMATIC FLUORIDES; ANTIBACTERIAL ACTIVITIES; REGIOSELECTIVE SYNTHESIS; 2+2 CYCLOADDUCTS; DERIVATIVES; CATALYSTS; CYCLOPENTADIENE; HYDROGENATION; BUTADIENES; AMINES;
D O I：
10.1007/s11172-021-3327-8
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The gas-phase copyrolysis of tetrafluoroethylene with buta-1,3-diene in a flow reactor at 495-505 degrees C produces 3,3,4,4-tetrafluorocyclohex-1-ene, which selectively converted to 1,2-difluorobenzene or 1-chloro-2,3-difluorobenzene. The latter can be converted to 2-chloro-3,4-difluoronitrobenzene, 2,3,4-trifluoronitrobenzene, 2,3-difluoro-6-nitrophenol, or 2-chloro-3-fluoro-4-nitrophenol via nitration, fluorodechlorination, and hydrolysis reactions.
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页码：2156 / 2163
页数：8
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