Redox and pH Dual-Responsive Supramolecular Micelles with a Traditional Polymer Block and a Supramolecular Block for Drug Controlled Release

被引：9

作者：

Zhang, Xiaojin ^{[1
]}

Zhuo, Renxi ^{[1
]}

机构：

[1] Wuhan Univ, Dept Chem, Minist Educ, Key Lab Biomed Polymers, Wuhan 430072, Peoples R China

来源：

MACROMOLECULAR CHEMISTRY AND PHYSICS | 2016年 / 217卷 / 17期

关键词：

cyclodextrin; host-guest interactions; micelles; pH-responsive; redox-responsive; COPOLYMER; DELIVERY; NANOPARTICLES; WATER; ASSEMBLIES; BEHAVIOR;

D O I：

10.1002/macp.201600172

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Redox and pH dual-responsive supramolecular micelles are prepared through a traditional polymer block and a supramolecular block to completely release the drugs. Ferrocene-introduced and hydrophobic-modified beta-cyclodextrin (beta-CD-Fc-Ace, where beta-CD, Fc, and Ace refer to beta-cyclodextrin, ferrocene, and acetal, respectively) is used to build the supramolecular block. Adamantane-terminated poly(ethylene glycol) methyl ether (mPEG-Ada) is the traditional polymer block. The average diameter of supramolecular micelles is approximate to 100 nm. Supramolecular micelles are able to control the release of the drugs in the cancer cells due to pH and redox microenvironments.

引用

页码：1926 / 1933

页数：8

共 50 条

[1] Supramolecular micelles with dual temperature and redox responses for multi-controlled drug release
Yuan, Weizhong
Zou, Hui
Guo, Wen
Shen, Tianxiang
Ren, Jie
POLYMER CHEMISTRY, 2013, 4 (09) : 2658 - 2661
[2] Salt/pH dual-responsive supramolecular brush copolymer micelles with molecular recognition of nucleobases for drug delivery
Wang, Dali
Huan, Xiuying
Zhu, Lijuan
Liu, Jinyao
Qiu, Feng
Yan, Deyue
Zhu, Xinyuan
RSC ADVANCES, 2012, 2 (31): : 11953 - 11962
[3] Redox-responsive Long Chain Supramolecular Hyperbranched Polymer for Controlled Drug Release
Liu, Ting-ting
Wang, Jing-xia
Song, Yan-li
Yuan, Hong-xing
Tian, Wei
ACTA POLYMERICA SINICA, 2018, (04): : 482 - 489
[4] Linear Supramolecular Block Copolymer Micelles for ROS-Responsive Release of Antimicrobial Pesticides
Su, Weihua
Qin, Yan
Wu, Jianning
Meng, Guihua
Yang, Shengchao
Cui, Lin
Liu, Zhiyong
Guo, Xuhong
ACS APPLIED NANO MATERIALS, 2023, 6 (14) : 12736 - 12743
[5] Preparation of pH/redox dual responsive polymeric micelles with enhanced stability and drug controlled release
Sang, Xinxin
Yang, Qiyi
Shi, Gang
Zhang, Liping
Wang, Dawei
Ni, Caihua
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2018, 91 : 727 - 733
[6] Temperature and pH Dual-Responsive Supramolecular Polymer Hydrogels Hybridized with Functional Inorganic Nanoparticles
Niu, Yanli
Yuan, Xiaoyan
Zhao, Yunhui
Zhang, Wenyu
Ren, Lixia
MACROMOLECULAR CHEMISTRY AND PHYSICS, 2017, 218 (09)
[7] Photo-Responsive Supramolecular Micelles for Controlled Drug Release and Improved Chemotherapy
Ilhami, Fasih Bintang
Peng, Kai-Chen
Chang, Yi-Shiuan
Alemayehu, Yihalem Abebe
Tsai, Hsieh-Chih
Lai, Juin-Yih
Chiao, Yu-Hsuan
Kao, Chen-Yu
Cheng, Chih-Chia
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (01) : 1 - 15
[8] pH and Glutathione Dual-Responsive Dynamic Cross-Linked Supramolecular Network on Mesoporous Silica Nanoparticles for Controlled Anticancer Drug Release
Li, Qing-Lan
Xu, Shi-Han
Zhou, Hang
Wang, Xin
Dong, Biao
Gao, Hui
Tang, Jun
Yang, Ying-Wei
ACS APPLIED MATERIALS & INTERFACES, 2015, 7 (51) : 28656 - 28664
[9] Design, fabrication and evaluation of redox/pH dual-responsive micelles for tumor targeting delivery and controlled release of paclitaxel
Xu, Yingxue
Liang, Na
Fu, Jia
Zong, Zhe
Long, Xueling
Sun, Shaoping
JOURNAL OF APPLIED POLYMER SCIENCE, 2023,
[10] Design, fabrication and evaluation of redox/pH dual-responsive micelles for tumor targeting delivery and controlled release of paclitaxel
Xu, Yingxue
Liang, Na
Fu, Jia
Zong, Zhe
Long, Xueling
Sun, Shaoping
JOURNAL OF APPLIED POLYMER SCIENCE, 2023, 140 (44)

← 1 2 3 4 5 →