The interplay of transcriptional and post-transcriptional regulation of migration of mesenchymal stem cells during early stages of bone fracture healing

被引：2
作者：
Dong, C. -H. [1 ]
Deng, Y. -S. [1 ]
Yang, X. -J. [1 ]
Liu, J. [2 ]
Liu, R. [3 ]
Hou, F. -Y. [1 ]
Li, S. -S. [1 ]
Zhen, P. [2 ]
机构：
[1] Lanzhou Gen Hosp, Ctr Orthoped Surg PLA, Dept Sports Med, Lanzhou, Gansu, Peoples R China
[2] Lanzhou Gen Hosp, Ctr Orthoped Surg PLA, Dept Joint Surg, Lanzhou, Gansu, Peoples R China
[3] Lanzhou Gen Hosp, Ctr Orthoped Surg PLA, Dept Traumat Surg, Lanzhou, Gansu, Peoples R China
来源：
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES | 2017年 / 21卷 / 24期
关键词：
Bone fracture; Bone fracture healing; Mesenchymal stem cells; NECROSIS-FACTOR-ALPHA; STROMAL CELLS; IN-VITRO; REPAIR; RECRUITMENT; EXPRESSION; CYTOKINES;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Bone fractures are a medical condition where the continuity of the bone is broken due to a fall or accident. The fracture may also be the result of medical conditions such as osteoporosis, cancers of bone or osteogenesis imperfect. During the bone fracture healing process, the mesenchymal stem cells (undifferentiated connective tissue cells) are recruited from local and systemic sources. The modulation of mesenchymal cell migration to the fractured site is the desired goal. Still, there are many processes that are still required to be studied and analyzed. We aimed to consolidate and review the available information on this topic.
引用
收藏
页码：5542 / 5547
页数：6
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