Combination Therapy for Extreme Drug-Resistant Acinetobacter baumannii: Ready for Prime Time?

被引：29
作者：
Spellberg, Brad [1 ,2 ]
Bonomo, Robert A. [3 ]
机构：
[1] Keck Sch Med USC, Div Infect Dis, Los Angeles, CA 90033 USA
[2] Los Angeles Cty USC Med Ctr, Los Angeles, CA USA
[3] Case Western Reserve Univ, Dept Pharmacol, Louis Stokes Cleveland Dept Vet Affairs Med Ctr, Dept Med,Dept Mol Biol & Microbiol, Cleveland, OH 44106 USA
来源：
CRITICAL CARE MEDICINE | 2015年 / 43卷 / 06期
关键词：
acinetobacter; antibiotics; combination therapy; ANTIBACTERIAL AGENTS; CLINICAL-OUTCOMES; RISK-FACTORS; INFECTIONS; TIGECYCLINE; BACTEREMIA; PNEUMONIA; MORTALITY; COLISTIN; SINGLE;
D O I：
10.1097/CCM.0000000000001029
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
引用
收藏
页码：1332 / 1334
页数：4
相关论文
共 22 条
[1]   Excess Mortality Associated With Colistin-Tigecycline Compared With Colistin-Carbapenem Combination Therapy for Extensively Drug-Resistant Acinetobacter baumannii Bacteremia: A Multicenter Prospective Observational Study [J].
Cheng, Aristine ;
Chuang, Yu-Chung ;
Sun, Hsin-Yun ;
Sheng, Wang-Huei ;
Yang, Chia-Jui ;
Liao, Chun-Hsing ;
Hsueh, Po-Ren ;
Yang, Jia-Ling ;
Shen, Ni-Jiin ;
Wang, Jann-Tay ;
Hung, Chien-Ching ;
Chen, Yee-Chun ;
Chang, Shan-Chwen .
CRITICAL CARE MEDICINE, 2015, 43 (06) :1194-1204
[2]   Effectiveness of tigecycline-based versus colistin-based therapy for treatment of pneumonia caused by multidrug-resistant Acinetobacter baumannii in a critical setting: a matched cohort analysis [J].
Chuang, Yu-Chung ;
Cheng, Chien-Yu ;
Sheng, Wang-Huei ;
Sun, Hsin-Yun ;
Wang, Jann-Tay ;
Chen, Yee-Chun ;
Chang, Shan-Chwen .
BMC INFECTIOUS DISEASES, 2014, 14
[3]   Colistin and Rifampicin Compared With Colistin Alone for the Treatment of Serious Infections Due to Extensively Drug-Resistant Acinetobacter baumannii: A Multicenter, Randomized Clinical Trial [J].
Durante-Mangoni, Emanuele ;
Signoriello, Giuseppe ;
Andini, Roberto ;
Mattei, Annunziata ;
De Cristoforo, Maria ;
Murino, Patrizia ;
Bassetti, Matteo ;
Malacarne, Paolo ;
Petrosillo, Nicola ;
Galdieri, Nicola ;
Mocavero, Paola ;
Corcione, Antonio ;
Viscoli, Claudio ;
Zarrilli, Raffaele ;
Gallo, Ciro ;
Utili, Riccardo .
CLINICAL INFECTIOUS DISEASES, 2013, 57 (03) :349-358
[4]   A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline [J].
Gordon, N. C. ;
Wareham, D. W. .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2009, 63 (04) :775-780
[5]   Efficacy and Safety Profile Comparison of Colistin and Tigecycline on the Extensively Drug Resistant Acinetobacter baumannii [J].
Kwon, Sung Hee ;
Ahn, Hye Lim ;
Han, Ok Yeon ;
La, Hyen O. .
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2014, 37 (03) :340-346
[6]   Risk Factors and Outcome Analysis of Acinetobacter baumannii Complex Bacteremia in Critical Patients* [J].
Lee, Hao-Yuan ;
Chen, Chyi-Liang ;
Wu, Si-Ru ;
Huang, Chih-Wei ;
Chiu, Cheng-Hsun .
CRITICAL CARE MEDICINE, 2014, 42 (05) :1081-1088
[7]   Carbapenem resistance and mortality in patients with Acinetobacter baumannii infection: systematic review and meta-analysis [J].
Lemos, E. V. ;
de la Hoz, F. P. ;
Einarson, T. R. ;
McGhan, W. F. ;
Quevedo, E. ;
Castaneda, C. ;
Kawai, K. .
CLINICAL MICROBIOLOGY AND INFECTION, 2014, 20 (05) :416-423
[8]  
Liu CP, 2014, J MICROBIOL IMMUNOL
[9]   Pharmacodynamics of Levofloxacin in a Murine Pneumonia Model of Pseudomonas aeruginosa Infection: Determination of Epithelial Lining Fluid Targets [J].
Louie, Arnold ;
Fregeau, Christine ;
Liu, Weiguo ;
Kulawy, Robert ;
Drusano, G. L. .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (08) :3325-3330
[10]  
Marchand CL, 2013, ASM BIOD EM DIS RES
123